Detalhe da pesquisa
1.
Dynamic tracing of sugar metabolism reveals the mechanisms of action of synthetic sugar analogs.
Glycobiology
; 32(3): 239-250, 2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34939087
2.
Sialic Acid Mimetics to Target the Sialic Acid-Siglec Axis.
Trends Biochem Sci
; 41(6): 519-531, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27085506
3.
Combined sialic acid and histone deacetylase (HDAC) inhibitor treatment up-regulates the neuroblastoma antigen GD2.
J Biol Chem
; 294(12): 4437-4449, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670592
4.
Disease mutations in CMP-sialic acid transporter SLC35A1 result in abnormal α-dystroglycan O-mannosylation, independent from sialic acid.
Hum Mol Genet
; 24(8): 2241-6, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25552652
5.
Metabolic sialic acid blockade lowers the activation threshold of moDCs for TLR stimulation.
Immunol Cell Biol
; 95(4): 408-415, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27874015
6.
Metabolic Oligosaccharide Engineering with Alkyne Sialic Acids Confers Neuraminidase Resistance and Inhibits Influenza Reproduction.
Bioconjug Chem
; 28(7): 1811-1815, 2017 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28635265
7.
Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry.
Angew Chem Int Ed Engl
; 56(12): 3309-3313, 2017 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28194834
8.
Specific labeling of newly synthesized lipopolysaccharide via metabolic incorporation of azido-galactose.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1869(4): 159467, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38382574
9.
Structure-Activity Relationship of Metabolic Sialic Acid Inhibitors and Labeling Reagents.
ACS Chem Biol
; 17(3): 590-597, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35179348
10.
Fighting Shigella by Blocking Its Disease-Causing Toxin.
J Med Chem
; 64(9): 6059-6069, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33909975
11.
Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids.
J Med Chem
; 62(2): 1014-1021, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30543426
12.
Selective Inhibition of Sialic Acid-Based Molecular Mimicry in Haemophilus influenzae Abrogates Serum Resistance.
Cell Chem Biol
; 25(10): 1279-1285.e8, 2018 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29983272
13.
Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell-Mediated Tumor Immunity.
Cancer Res
; 78(13): 3574-3588, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29703719
14.
NANS-mediated synthesis of sialic acid is required for brain and skeletal development.
Nat Genet
; 48(7): 777-84, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27213289
15.
Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands.
ACS Chem Biol
; 10(10): 2353-63, 2015 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26258433