Detalhe da pesquisa
1.
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs.
Nature
; 575(7781): 229-233, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31666694
2.
BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.
Blood
; 139(19): 2983-2997, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35226736
3.
Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein in testis carcinoma and other cancers: Results of a Phase I/II open-label, dose escalation study.
Int J Cancer
; 150(6): 993-1006, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34724226
4.
Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST.
Br J Cancer
; 127(11): 2072-2085, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36175617
5.
Gastrointestinal stromal tumor enhancers support a transcription factor network predictive of clinical outcome.
Proc Natl Acad Sci U S A
; 115(25): E5746-E5755, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866822
6.
YWHAE-rearranged high-grade endometrial stromal sarcoma: Two-center case series and response to chemotherapy.
Gynecol Oncol
; 145(3): 531-535, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28390819
7.
ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs.
Cancer Res
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38657118
8.
Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity.
Nat Genet
; 33(4): 477-85, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12640454
9.
MOZ and Menin-MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor.
Cancer Discov
; 12(7): 1804-1823, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35499757
10.
Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression.
Clin Cancer Res
; 28(11): 2397-2408, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35325095
11.
Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
PLoS Biol
; 6(10): e257, 2008 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-18942891
12.
HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor.
Clin Cancer Res
; 27(6): 1706-1719, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33451979
13.
Unmet Medical Needs and Future Perspectives for Leiomyosarcoma Patients-A Position Paper from the National LeioMyoSarcoma Foundation (NLMSF) and Sarcoma Patients EuroNet (SPAEN).
Cancers (Basel)
; 13(4)2021 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33672607
14.
Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate.
Cancer Discov
; 11(6): 1508-1523, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579785
15.
Oncogenic Gene-Expression Programs in Leiomyosarcoma and Characterization of Conventional, Inflammatory, and Uterogenic Subtypes.
Mol Cancer Res
; 18(9): 1302-1314, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32518213
16.
Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease.
JCO Precis Oncol
; 20192019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30793095
17.
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition.
Cancer Res
; 79(5): 994-1009, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30630822
18.
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma.
Elife
; 72018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30431433
19.
Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.
PLoS Med
; 4(8): e262, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17760499
20.
Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of NTRK1.
JCO Precis Oncol
; 4: 79-90, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32133433