Detalhe da pesquisa
1.
Base-editing mutagenesis maps alleles to tune human T cell functions.
Nature
; 625(7996): 805-812, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38093011
2.
Maternal- and Fetal-Encoded Perforin-2 Limits Placental Infection by a Bloodborne Pathogen.
J Immunol
; 205(7): 1878-1885, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32839236
3.
Sustained IL-2R signaling of limited duration by high-dose mIL-2/mCD25 fusion protein amplifies tumor-reactive CD8+ T cells to enhance antitumor immunity.
Cancer Immunol Immunother
; 70(4): 909-921, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037893
4.
Robust IL-2-dependent antitumor immunotherapy requires targeting the high-affinity IL-2R on tumor-specific CD8+ T cells.
J Immunother Cancer
; 11(6)2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37270181
5.
Fueling Cancer Vaccines to Improve T Cell-Mediated Antitumor Immunity.
Front Oncol
; 12: 878377, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35651800
6.
Engineering IL-2 for immunotherapy of autoimmunity and cancer.
Nat Rev Immunol
; 22(10): 614-628, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217787
7.
High-dose IL-2/CD25 fusion protein amplifies vaccine-induced CD4+ and CD8+ neoantigen-specific T cells to promote antitumor immunity.
J Immunother Cancer
; 9(9)2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475132
8.
Acute Lipopolysaccharide-Induced Inflammation Lowers IL-2R Signaling and the Proliferative Potential of Regulatory T Cells.
Immunohorizons
; 4(12): 809-824, 2020 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33334814
9.
Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms.
Diabetes
; 69(11): 2400-2413, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32843568
10.
Chromosomally-Encoded Yersinia pestis Type III Secretion Effector Proteins Promote Infection in Cells and in Mice.
Front Cell Infect Microbiol
; 9: 23, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30854334