Detalhe da pesquisa
1.
C3HeB/FeJ Mice mimic many aspects of gene expression and pathobiological features of human hepatocellular carcinoma.
Mol Carcinog
; 58(3): 309-320, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30365185
2.
Human O6 -methylguanine-DNA methyltransferase containing C145A does not prevent hepatocellular carcinoma in C3HeB/FeJ transgenic mice.
Mol Carcinog
; 52(4): 275-85, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22213062
3.
DNA Alkylating Agent Protects Against Spontaneous Hepatocellular Carcinoma Regardless of O6-Methylguanine-DNA Methyltransferase Status.
Cancer Prev Res (Phila)
; 9(3): 245-52, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26667451
4.
Apoptosis induction by the dual-action DNA- and protein-reactive antitumor drug irofulven is largely Bcl-2-independent.
Biochem Pharmacol
; 65(4): 503-13, 2003 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12566077
5.
Irofulven induces apoptosis in breast cancer cells regardless of caspase-3 status.
Breast Cancer Res Treat
; 71(2): 133-43, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11883439
6.
The genome factor in region-specific DNA damage: the DNA-reactive drug U-78779 prefers mixed A/T-G/C sequences at the nucleotide level but is region-specific for long pure AT islands at the genomic level.
Biochemistry
; 41(5): 1545-55, 2002 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-11814348