Detalhe da pesquisa
1.
Intraluminal pressure elevates intracellular calcium and contracts CNS pericytes: Role of voltage-dependent calcium channels.
Proc Natl Acad Sci U S A
; 120(9): e2216421120, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36802432
2.
Uncoupling of Ca2+ sparks from BK channels in cerebral arteries underlies hypoperfusion in hypertension-induced vascular dementia.
Proc Natl Acad Sci U S A
; 120(33): e2307513120, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37549299
3.
Functionally linked potassium channel activity in cerebral endothelial and smooth muscle cells is compromised in Alzheimer's disease.
Proc Natl Acad Sci U S A
; 119(26): e2204581119, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35727988
4.
Distinct potassium channel types in brain capillary pericytes.
Biophys J
; 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38444160
5.
Piezo1 Is a Mechanosensor Channel in Central Nervous System Capillaries.
Circ Res
; 130(10): 1531-1546, 2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35382561
6.
PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity.
Proc Natl Acad Sci U S A
; 118(17)2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875602
7.
The post-arteriole transitional zone: a specialized capillary region that regulates blood flow within the CNS microvasculature.
J Physiol
; 601(5): 889-901, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36751860
8.
PIP2: A critical regulator of vascular ion channels hiding in plain sight.
Proc Natl Acad Sci U S A
; 117(34): 20378-20389, 2020 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32764146
9.
Contractile pericytes determine the direction of blood flow at capillary junctions.
Proc Natl Acad Sci U S A
; 117(43): 27022-27033, 2020 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33051294
10.
Epidermal Growth Factor Receptors in Vascular Endothelial Cells Contribute to Functional Hyperemia in the Brain.
Int J Mol Sci
; 24(22)2023 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38003472
11.
Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion.
Proc Natl Acad Sci U S A
; 115(15): E3569-E3577, 2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29581272
12.
The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction.
Proc Natl Acad Sci U S A
; 113(2): E229-38, 2016 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26627720
13.
The yin and yang of KV channels in cerebral small vessel pathologies.
Microcirculation
; 25(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29247493
14.
Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.
Proc Natl Acad Sci U S A
; 112(7): E796-805, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25646445
15.
Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function.
Proc Natl Acad Sci U S A
; 111(20): 7462-7, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24808139
16.
TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses.
Proc Natl Acad Sci U S A
; 110(15): 6157-62, 2013 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23530219
17.
Vascular TRP channels: performing under pressure and going with the flow.
Physiology (Bethesda)
; 29(5): 343-60, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25180264
18.
Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL.
J Clin Invest
; 134(8)2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38386425
19.
Epidermal growth factor receptors in vascular endothelial cells contribute to functional hyperemia in the brain.
bioRxiv
; 2023 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37745396
20.
Adenosine signaling activates ATP-sensitive K+ channels in endothelial cells and pericytes in CNS capillaries.
Sci Signal
; 15(727): eabl5405, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35349300