Detalhe da pesquisa
1.
Meta-Analysis of 49 Roche Oncology Trials Comparing Blinded Independent Central Review (BICR) and Local Evaluation to Assess the Value of BICR.
Oncologist
; 2023 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36905580
2.
Calibration of in vitro multidrug resistance protein 1 substrate and inhibition assays as a basis to support the prediction of clinically relevant interactions in vivo.
Drug Metab Dispos
; 42(9): 1411-22, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24939652
3.
Modeling air-to-air communication networks in the North Atlantic region.
CEAS Aeronaut J
; 14(2): 569-589, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214203
4.
Comparative evaluation of in silico systems for ames test mutagenicity prediction: scope and limitations.
Chem Res Toxicol
; 24(6): 843-54, 2011 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21534561
5.
Translational PK/PD modeling for cardiovascular safety assessment of drug candidates: Methods and examples in drug development.
J Pharmacol Toxicol Methods
; 70(1): 73-85, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24879942
6.
PK/PD assessment in CNS drug discovery: Prediction of CSF concentration in rodents for P-glycoprotein substrates and application to in vivo potency estimation.
Biochem Pharmacol
; 85(11): 1684-99, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23454189
7.
Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste.
Angew Chem Int Ed Engl
; 46(40): 7697-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17705204
8.
Can we discover pharmacological promiscuity early in the drug discovery process?
Drug Discov Today
; 17(7-8): 325-35, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22269136
9.
Arabidopsis thaliana expresses a second functional flavonol synthase.
FEBS Lett
; 583(12): 1981-6, 2009 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19433090
10.
Use of 3D QSAR models for database screening: a feasibility study.
J Chem Inf Model
; 48(2): 384-96, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18211050
11.
Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.
ChemMedChem
; 3(8): 1217-31, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18470859
12.
Use of biotin derivatives to probe conformational changes in proteins.
J Biol Chem
; 282(30): 21609-17, 2007 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-17545162
13.
Integrated approach using protein and ligand information to analyze selectivity- and affinity-determining features of carbonic anhydrase isozymes.
ChemMedChem
; 1(8): 839-53, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16902938