Detalhe da pesquisa
1.
Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues.
J Med Chem
; 45(5): 1052-63, 2002 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-11855985
2.
Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials.
J Med Chem
; 46(23): 4933-45, 2003 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-14584944
3.
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
J Med Chem
; 52(5): 1408-15, 2009 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19222165
4.
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
J Med Chem
; 52(7): 1828-44, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19284751