Detalhe da pesquisa
1.
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical MatterâCompounds with Novel Mechanisms from High-Throughput Screening Profiles.
ACS Chem Biol
; 19(4): 938-952, 2024 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565185
2.
DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery.
ACS Chem Biol
; 17(6): 1401-1414, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508359
3.
Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins.
Neurobiol Dis
; 36(2): 320-30, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19660549
4.
Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes.
Cell Rep
; 27(2): 616-630.e6, 2019 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30970262
5.
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery.
Nat Commun
; 9(1): 4307, 2018 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333485
6.
PIK3CA mutations in intraductal papillary mucinous neoplasm/carcinoma of the pancreas.
Clin Cancer Res
; 12(12): 3851-5, 2006 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16778113
7.
PIK3CA mutations in head and neck squamous cell carcinoma.
Clin Cancer Res
; 12(5): 1441-6, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16533766
8.
ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157.
Neurosci Lett
; 660: 109-114, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923481
9.
Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease.
Genome Med
; 8(1): 5, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26803900
10.
Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection.
Cell Stem Cell
; 19(6): 703-708, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27912091
11.
Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease.
Antioxid Redox Signal
; 16(9): 855-68, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21529244
12.
Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease.
Exp Neurol
; 225(1): 74-84, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20561979
13.
Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition.
Free Radic Biol Med
; 47(7): 1019-27, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19596066
14.
Mutational analyses of multiple oncogenic pathways in intraductal papillary mucinous neoplasms of the pancreas.
Pancreas
; 36(2): 168-72, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18376308