RESUMO
Ultraviolet (UV) radiation from sunlight has various adverse effects; thus, UV blockage is recommended for preventing sunburn. Common sunscreen ingredients, such as nanosized titanium dioxide and zinc oxide, offer effective protection and enhance cosmetic appearance; however, health concerns have been raised regarding their photocatalytic activity, which generates reactive oxygen species under UV illumination. Silver nanoparticles (AgNPs) are known as safe materials for use in a wide spectrum of biomedical applications. In vitro studies have revealed that AgNPs may have a protective effect against UV irradiation, but the effects in animal studies remain unclear. The present study demonstrated that AgNPs effectively protect against UVB-induced skin damage both in cell cultures and mouse models. These results suggested that AgNPs are feasible and safe as sunscreen ingredients for protection against UVB-induced skin damage.
Assuntos
Nanopartículas Metálicas , Prata/farmacologia , Pele/efeitos dos fármacos , Pele/efeitos da radiação , Protetores Solares/farmacologia , Raios Ultravioleta/efeitos adversos , Animais , Células HaCaT , Humanos , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Luz Solar/efeitos adversosRESUMO
A thermally activated delayed fluorescent (TADF) emitter (DMAC-TRZ) was reported either as the emitting dopant in a host or as the non-doped (neat) emitting layer to achieve high EL EQEs of up to 26.5% and 20% in OLEDs, respectively.