Detalhe da pesquisa
1.
Improved Cardiac Function in Postischemic Rats Using an Optimized Cardiac Reprogramming Cocktail Delivered in a Single Novel Adeno-Associated Virus.
Circulation
; 148(14): 1099-1112, 2023 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37602409
2.
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Nature
; 545(7654): 360-364, 2017 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28489825
3.
COP1, a negative regulator of photomorphogenesis, positively regulates plant disease resistance via double-stranded RNA binding proteins.
PLoS Pathog
; 14(3): e1006894, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29513740
4.
The analogous and opposing roles of double-stranded RNA-binding proteins in bacterial resistance.
J Exp Bot
; 70(5): 1627-1638, 2019 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30843586
5.
DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice.
Carcinogenesis
; 36(1): 115-21, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25355291
6.
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors.
Proc Natl Acad Sci U S A
; 109(29): 11717-22, 2012 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753465
7.
Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice.
Nat Commun
; 15(1): 1352, 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38409164
8.
AAV9:PKP2 improves heart function and survival in a Pkp2-deficient mouse model of arrhythmogenic right ventricular cardiomyopathy.
Commun Med (Lond)
; 4(1): 38, 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38499690
9.
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23.
Nat Genet
; 31(2): 133-4, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12021784
10.
Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene.
Cancer Cell
; 3(3): 297-302, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12676587
11.
The prognostic role of a gene signature from tumorigenic breast-cancer cells.
N Engl J Med
; 356(3): 217-26, 2007 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17229949
12.
Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs.
PLoS One
; 15(3): e0229445, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32160239
13.
RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.
Sci Rep
; 7(1): 15270, 2017 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29127379
14.
WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death.
Sci Adv
; 3(6): e1700090, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28691093
15.
Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.
Biochem J
; 390(Pt 1): 125-36, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15839837
16.
PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.
Cancer Res
; 62(19): 5420-4, 2002 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12359748
17.
Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates ß-Catenin Signaling and Tumorigenesis in Multiple Cancer Types.
Cancer Res
; 76(3): 713-23, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26719531
18.
Wip1-deficient mice are resistant to common cancer genes.
Trends Mol Med
; 10(8): 359-61, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15310454
19.
Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Clin Cancer Res
; 21(9): 2084-95, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934888
20.
NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells.
Cancer Res
; 74(7): 2106-18, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24525742