Detalhe da pesquisa
1.
Impact of PKCε downregulation on autophagy in glioblastoma cells.
BMC Cancer
; 18(1): 185, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29439667
2.
Zapotin (5,6,2',6'-tetramethoxyflavone) Modulates the Crosstalk Between Autophagy and Apoptosis Pathways in Cancer Cells with Overexpressed Constitutively Active PKCϵ.
Nutr Cancer
; 68(2): 290-304, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26847268
3.
Synthesis, cytotoxic, and antitumor activities of 2-pyridylhydrazones derived from 3-benzoylpyridazines.
Arch Pharm (Weinheim)
; 347(8): 599-608, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24917378
4.
Telomerase downregulation induces proapoptotic genes expression and initializes breast cancer cells apoptosis followed by DNA fragmentation in a cell type dependent manner.
Mol Biol Rep
; 40(8): 4995-5004, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23677713
5.
N-benzoxazol-2-yl-N'-1-(isoquinolin-3-yl-ethylidene)-hydrazine, a novel compound with antitumor activity, induces radicals and dissipation of mitochondrial membrane potential.
Invest New Drugs
; 27(3): 189-202, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18612590
6.
Synthesis, structure-activity relationships, and antitumor studies of 2-benzoxazolyl hydrazones derived from alpha-(N)-acyl heteroaromatics.
J Med Chem
; 49(21): 6343-50, 2006 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17034140
7.
A cold-active extracellular metalloprotease from Pedobacter cryoconitis--production and properties.
Res Microbiol
; 156(4): 499-505, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15862448
8.
Protein kinase C isozymes as potential targets for anticancer therapy.
Curr Cancer Drug Targets
; 4(2): 125-46, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15032665
9.
Thienoquinolines as novel disruptors of the PKCε/RACK2 protein-protein interaction.
J Med Chem
; 57(8): 3235-46, 2014 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24712764
10.
The tetramethoxyflavone zapotin selectively activates protein kinase C epsilon, leading to its down-modulation accompanied by Bcl-2, c-Jun and c-Fos decrease.
Eur J Pharmacol
; 682(1-3): 21-8, 2012 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22381066
11.
Modulators of protein-protein interactions: novel approaches in targeting protein kinases and other pharmaceutically relevant biomolecules.
Curr Top Med Chem
; 11(11): 1305-19, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21513500
12.
Oleanolic acid derivative methyl 3,11-dioxoolean-12-en-28-olate targets multidrug resistance related to ABCB1.
Pharmacol Rep
; 63(6): 1500-17, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22358098
13.
Barbituric acid derivative BAS 02104951 inhibits PKCε, PKCη, PKCε/RACK2 interaction, Elk-1 phosphorylation in HeLa and PKCε and η translocation in PC3 cells following TPA-induction.
J Biochem
; 149(3): 331-6, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21186251
14.
Protein kinase Cgamma in colon cancer cells: expression, Thr514 phosphorylation and sensitivity to butyrate-mediated upregulation as related to the degree of differentiation.
Chem Biol Interact
; 185(1): 25-32, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20188713
15.
Dehydroepiandrosterone sulfate directly activates protein kinase C-beta to increase human neutrophil superoxide generation.
Mol Endocrinol
; 24(4): 813-21, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20172962
16.
Signal transduction of constitutively active protein kinase C epsilon.
Cell Signal
; 21(5): 745-52, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19168130
17.
Human platelets attenuate Aspergillus species via granule-dependent mechanisms.
J Infect Dis
; 198(8): 1243-6, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18752432
18.
Novel boronated derivatives of 5,10,15,20-tetraphenylporphyrin: synthesis and toxicity for drug-resistant tumor cells.
Bioorg Med Chem
; 14(1): 109-20, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16185886