Detalhe da pesquisa
1.
DNA-Based Delivery of Checkpoint Inhibitors in Muscle and Tumor Enables Long-Term Responses with Distinct Exposure.
Mol Ther
; 28(4): 1068-1077, 2020 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101701
2.
State of play and clinical prospects of antibody gene transfer.
J Transl Med
; 15(1): 131, 2017 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28592330
3.
Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer antigen 125.
Cancer
; 120(21): 3311-9, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24989332
4.
Exploring the Fate of Antibody-Encoding pDNA after Intramuscular Electroporation in Mice.
Pharmaceutics
; 15(4)2023 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37111645
5.
Serum mesothelin and megakaryocyte potentiating factor in pancreatic and biliary cancers.
Clin Chem Lab Med
; 50(4): 721-5, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22149739
6.
Intratumoral DNA-based delivery of checkpoint-inhibiting antibodies and interleukin 12 triggers T cell infiltration and anti-tumor response.
Cancer Gene Ther
; 29(7): 984-992, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34754076
7.
Clinically relevant dosing and pharmacokinetics of DNA-encoded antibody therapeutics in a sheep model.
Front Oncol
; 12: 1017612, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36263202
8.
Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model.
iScience
; 25(8): 104705, 2022 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35813873
9.
Fibulin-3 as a biomarker for pleural mesothelioma.
N Engl J Med
; 368(2): 189, 2013 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23301744
10.
Diagnostic performance of soluble mesothelin and megakaryocyte potentiating factor in mesothelioma.
Am J Respir Crit Care Med
; 181(6): 620-5, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20075387
11.
Improved Potency and Safety of DNA-Encoded Antibody Therapeutics Through Plasmid Backbone and Expression Cassette Engineering.
Hum Gene Ther
; 32(19-20): 1200-1209, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34482757
12.
DNA-based delivery of anti-DR5 Nanobodies improves exposure and anti-tumor efficacy over protein-based administration.
Cancer Gene Ther
; 28(7-8): 828-838, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32733055
13.
Electroporation outperforms in vivo-jetPEI for intratumoral DNA-based reporter gene transfer.
Sci Rep
; 10(1): 19532, 2020 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177564
14.
Bridging the Clinical Gap for DNA-Based Antibody Therapy Through Translational Studies in Sheep.
Hum Gene Ther
; 30(11): 1431-1443, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31382777
15.
Prolonged in vivo expression and anti-tumor response of DNA-based anti-HER2 antibodies.
Oncotarget
; 9(17): 13623-13636, 2018 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29568382
16.
Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes.
Oncotarget
; 8(6): 9189-9199, 2017 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27999204
17.
Quantification of recombinant immunotoxin delivery to solid tumors allows for direct comparison of in vivo and in vitro results.
Sci Rep
; 5: 10832, 2015 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26111884
18.
Methylation-associated partial down-regulation of mesothelin causes resistance to anti-mesothelin immunotoxins in a pancreatic cancer cell line.
PLoS One
; 10(3): e0122462, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25803818
19.
Glomerular filtration rate is a confounder for the measurement of soluble mesothelin in serum.
Clin Chem
; 55(7): 1431-3, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19406915
20.
Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells.
J Immunother
; 37(1): 8-15, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316551