Detalhe da pesquisa
1.
Induced pluripotent stem cell-based assays recapture multiple properties of human astrocytes.
J Cell Mol Med
; 28(7): e18214, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509731
2.
Histopathological changes of the spinal cord and motor neuron dynamics in SOD1 Tg mice.
J Toxicol Pathol
; 35(1): 129-133, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35221507
3.
Genome-wide siRNA screening reveals that DCAF4-mediated ubiquitination of optineurin stimulates autophagic degradation of Cu,Zn-superoxide dismutase.
J Biol Chem
; 295(10): 3148-3158, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014991
4.
SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.
Mol Cell
; 52(1): 75-86, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076220
5.
The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.
Hum Mol Genet
; 25(2): 245-53, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26604152
6.
Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death.
Mol Cell
; 36(5): 805-18, 2009 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20005844
7.
Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.
J Neurosci
; 35(24): 9088-105, 2015 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085633
8.
[Zinc depletion and ER stress].
Nihon Rinsho
; 74(7): 1228-33, 2016 Jul.
Artigo
em Japonês
| MEDLINE | ID: mdl-27455816
9.
A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.
Neurobiol Dis
; 82: 478-486, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26297318
10.
A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.
Ann Neurol
; 72(5): 739-49, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23280792
11.
ASK1 promotes uterine inflammation leading to pathological preterm birth.
Sci Rep
; 10(1): 1887, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024889
12.
A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.
Nat Commun
; 9(1): 2668, 2018 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29991716
13.
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Sci Transl Med
; 9(391)2017 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28539470
14.
SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.
Adv Biol Regul
; 60: 95-104, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26563614
15.
Targeting ASK1 in ER stress-related neurodegenerative diseases.
Expert Opin Ther Targets
; 13(6): 653-64, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19456270