Detalhe da pesquisa
1.
Toxicokinetics of α-thujone following intravenous and gavage administration of α-thujone or α- and ß-thujone mixture in male and female F344/N rats and B6C3F1 mice.
Toxicol Appl Pharmacol
; 271(2): 216-28, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23669748
2.
Toxicokinetics of methyleugenol in F344 rats and B6C3F1 mice.
Xenobiotica
; 43(3): 293-302, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22876784
3.
Toxicokinetics of isoeugenol in F344 rats and B6C3F1 mice.
Xenobiotica
; 43(11): 1010-7, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23627552
4.
Evaluations of in vitro metabolism, drug-drug interactions mediated by reversible and time-dependent inhibition of CYPs, and plasma protein binding of MMB4 DMS.
Int J Toxicol
; 32(4 Suppl): 75S-87S, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929452
5.
Efficacy and pharmacokinetic/pharmacodynamic study of 1,1'-methylenebis{4-[(hydroxyimino)methyl] pyridinium} dimethanesulfonate in guinea pigs and rhesus macaques exposed to cyclosarin.
Int J Toxicol
; 32(4 Suppl): 108S-17S, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929444
6.
Absorption, distribution, metabolism, and excretion of 14C-MMB4 DMS administered intramuscularly to Sprague-Dawley rats and New Zealand White rabbits.
Int J Toxicol
; 32(4 Suppl): 88S-98S, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929453
7.
In vivo acetylcholinesterase reactivation in male guinea pigs and rhesus macaques following cyclosarin exposure and treatment with 1,1'-methylenebis{4-[(hydroxyimino)methyl] pyridinium} dimethanesulfonate.
Int J Toxicol
; 32(4 Suppl): 99S-107S, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929454
8.
Pharmacokinetics of MMB4 DMS in rats, rabbits, and dogs following a single IV administration.
Int J Toxicol
; 32(4 Suppl): 30S-7S, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929447
9.
Comparative toxicokinetics of MMB4 DMS in rats, rabbits, dogs, and monkeys following single and repeated intramuscular administration.
Int J Toxicol
; 32(4 Suppl): 38S-48S, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929448
10.
Pharmacokinetic modeling optimizes inhibition of the 'undruggable' EWS-FLI1 transcription factor in Ewing Sarcoma.
Oncotarget
; 5(2): 338-50, 2014 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24481407
11.
Effects of tyrosine kinase inhibitors on rat isolated heart function and protein biomarkers indicative of toxicity.
J Pharmacol Toxicol Methods
; 68(1): 150-9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23660125
12.
Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.
Oncotarget
; 3(2): 172-82, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22383402
13.
Human safety and pharmacokinetic study of intramuscular midazolam administered by autoinjector.
J Clin Pharmacol
; 50(10): 1128-35, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20466872