Detalhe da pesquisa
1.
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.
Nature
; 543(7644): 248-251, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28151488
2.
Lipid Nanoparticle Systems for Enabling Gene Therapies.
Mol Ther
; 25(7): 1467-1475, 2017 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28412170
3.
Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals.
Mol Ther
; 23(9): 1456-64, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26050989
4.
Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics.
Mol Ther
; 21(8): 1570-8, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23799535
5.
Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.
Mol Ther
; 19(12): 2186-200, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21971424
6.
Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.
Angew Chem Int Ed Engl
; 51(34): 8529-33, 2012 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22782619
7.
Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.
Mol Ther
; 18(7): 1357-64, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20461061
8.
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema.
Nat Commun
; 12(1): 3460, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34103491
9.
The combination of stabilized plasmid lipid particles and lipid nanoparticle encapsulated CpG containing oligodeoxynucleotides as a systemic genetic vaccine.
J Gene Med
; 11(1): 14-25, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19003796
10.
Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques.
Mol Ther Nucleic Acids
; 15: 36-47, 2019 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30974332
11.
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake.
J Control Release
; 291: 106-115, 2018 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30336167
12.
Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies.
Nat Commun
; 9(1): 3361, 2018 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30135514
13.
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.
J Exp Med
; 215(6): 1571-1588, 2018 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29739835
14.
Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines.
NPJ Vaccines
; 2: 29, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29263884
15.
mRNA mediates passive vaccination against infectious agents, toxins, and tumors.
EMBO Mol Med
; 9(10): 1434-1447, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28794134
16.
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge.
Nat Commun
; 8: 14630, 2017 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28251988
17.
Pieter Cullis' quest for a lipid-based, fusogenic delivery system for nucleic acid therapeutics: success with siRNA so what about mRNA?
J Drug Target
; 24(9): 774-779, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27588674
18.
Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity.
J Pharm Sci
; 94(5): 1024-38, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15793796
19.
Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes.
J Control Release
; 217: 345-51, 2015 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26264835
20.
Enhancing siRNA delivery by employing lipid nanoparticles.
Ther Deliv
; 5(6): 663-73, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25090280