Detalhe da pesquisa
1.
DeepCOP: deep learning-based approach to predict gene regulating effects of small molecules.
Bioinformatics
; 36(3): 813-818, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504186
2.
ETS transcription factors as emerging drug targets in cancer.
Med Res Rev
; 40(1): 413-430, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30927317
3.
Computer-Aided Discovery of Small Molecule Inhibitors of Thymocyte Selection-Associated High Mobility Group Box Protein (TOX) as Potential Therapeutics for Cutaneous T-Cell Lymphomas.
Molecules
; 24(19)2019 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31554191
4.
Toxic Colors: The Use of Deep Learning for Predicting Toxicity of Compounds Merely from Their Graphic Images.
J Chem Inf Model
; 58(8): 1533-1543, 2018 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30063345
5.
Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1.
J Cell Sci
; 128(15): 2938-50, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26092939
6.
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
J Biol Chem
; 289(38): 26417-26429, 2014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25086042
7.
The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV).
Nucleic Acids Res
; 41(22): 10062-76, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23990327
8.
Prioritizing disease-linked variants, genes, and pathways with an interactive whole-genome analysis pipeline.
Hum Mutat
; 35(5): 537-47, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24478219
9.
Polycomb repressive complex 2 regulates normal development of the mouse heart.
Circ Res
; 110(3): 406-15, 2012 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22158708
10.
Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer.
Sci Rep
; 14(1): 7082, 2024 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38528115
11.
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
J Biol Chem
; 292(10): 4359, 2017 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283588
12.
gSearch: a fast and flexible general search tool for whole-genome sequencing.
Bioinformatics
; 28(16): 2176-7, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22730434
13.
CompleteMOTIFs: DNA motif discovery platform for transcription factor binding experiments.
Bioinformatics
; 27(5): 715-7, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21183585
14.
Taxonomizing, sizing, and overcoming the incidentalome.
Genet Med
; 14(4): 399-404, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323072
15.
Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.
J Proteome Res
; 10(3): 1139-50, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21166474
16.
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
J Biol Chem
; 290(43): 25850, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26500294
17.
Identification of pyruvate kinase in methicillin-resistant Staphylococcus aureus as a novel antimicrobial drug target.
Antimicrob Agents Chemother
; 55(5): 2042-53, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21357306
18.
Deep Modeling of Regulating Effects of Small Molecules on Longevity-Associated Genes.
Pharmaceuticals (Basel)
; 14(10)2021 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681172
19.
Drugging the 'undruggable'. Therapeutic targeting of protein-DNA interactions with the use of computer-aided drug discovery methods.
Drug Discov Today
; 26(11): 2660-2679, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34332092
20.
Rapid Identification of Potential Inhibitors of SARS-CoV-2 Main Protease by Deep Docking of 1.3â Billion Compounds.
Mol Inform
; 39(8): e2000028, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32162456