Long-term effects of blue-blocking spectacle lenses on color perception.

The use of blue-blocking filters is increasing in spectacle lens users. Despite the low absorption in the blue range, some users complain about these filters because they affect their color perception. In a pilot study we have evaluated how the long-term use of 8 different blue-blocking filters impact the color perception during more than 2 weeks on a group of 18 normal color vision observers, compared with a control group of 10 observers. The evaluation was done using the FM100, the Color Assessment and Diagnosis (CAD) and an achromatic point measurement. Our results show that there is a trend to worsen with the filters on.

Color vision deficiencies and camouflage: a comparative study between normal and CVD observers.

There is a belief that observers with color vision deficiencies (CVD) perform better in detecting camouflaged objects than normal observers. Some studies have concluded contradictory findings when studying the performance of normal and CVD observers in the camouflage detection tasks in different conditions. This work presents a literature review on this topic, dividing it into three different and contradictory types of results: better performance for CVD, for normal observers, or same performance. Besides, two psychophysical experiments have been designed and carried out in a calibrated computer monitor on both normal and CVD human observers to measure the searching times of the different types of observers needed to find camouflaged stimuli in two different types of stimuli. Results show the trend that, in our experimental conditions, normal observers need shorter searching times than CVD observers in finding camouflaged stimuli both in images of natural scenes and in images with synthetic stimuli.

Metasurface-based contact lenses for color vision deficiency: comment.

Recently Karepov and Ellenbogen [Opt. Lett.45, 1379 (2020)OPLEDP0146-959210.1364/OL.384970] claimed that a new metasurface-based contact lens is able to correct deuteranomaly. Unfortunately, their results are not supported by psychophysical experiments, and some key assumptions in their simulations were misinterpreted. All of this has led to wrong conclusions providing false expectations to the color vision deficiency community.

Spectral Filter Selection for Increasing Chromatic Diversity in CVD Subjects.

This paper analyzes, through computational simulations, which spectral filters increase the number of discernible colors (NODC) of subjects with normal color vision, as well as red-green anomalous trichromats and dichromats. The filters are selected from a set of filters in which we have modeled spectral transmittances. With the selected filters we have carried out simulations performed using the spectral reflectances captured either by a hyperspectral camera or by a spectrometer. We have also studied the effects of these filters on color coordinates. Finally, we have simulated the results of two widely used color blindness tests: Ishihara and Farnsworth-Munsell 100 Hue (FM100). In these analyses the selected filters are compared with the commercial filters from EnChroma and VINO companies. The results show that the increase in NODC with the selected filters is not relevant. The simulation results show that none of these chosen filters help color vision deficiency (CVD) subjects to pass the set of color blindness tests studied. These results obtained using standard colorimetry support the hypothesis that the use of color filters does not cause CVDs to have a perception similar to that of a normal observer.

Assessment of VINO filters for correcting red-green Color Vision Deficiency.

In our ongoing research on the effectiveness of different passive tools for aiding Color Vision Deficiency (CVD) subjects, we have analyzed the VINO 02 Amp Oxy-Iso glasses using two strategies: 1) 52 observers were studied using four color tests (recognition, arrangement, discrimination, and color-naming); 2) the spectral transmittance of the lenses were used to model the color appearance of natural scenes for different simulated CVD subjects. We have also compared VINO and EnChroma glasses. The spectral transmission of the VINO glasses significantly changed color appearance. This change would allow some CVD subjects, above all the deutan ones, to be able to pass recognition tests but not the arrangement tests. To sum up, our results support the hypothesis that glasses with filters are unable to effectively resolve the problems related to color vision deficiency.

Psychiatrists and mental health activism during the final phase of the Franco regime and the democratic transition.

In the final years of the Franco dictatorship and during the period known as the democratic transition, there were a significant number of protests in the sphere of mental health in Spain. This article analyses the origins and functioning of the Psychiatric Network, which emerged in 1971, its connection to the formation of professional organizations and its role in the reception of anti-psychiatry ideas in Spain. We reach the conclusion that, although the Network's activities took place within a left-wing political and ideological framework, and at such an important time of social change as the end of the dictatorship, its discourse and practices always demonstrated a marked professional approach.

The beginning of Francoist psychiatry: the National Neurology and Psychiatry Conference (Barcelona, 1942).

While there has been some research into Francoist psychiatry, much work still needs to be done on the reorganization of the mental health profession within the new state. Held in Barcelona on 12, 13 and 14th January 1942, the National Neurology and Psychiatry Conference undoubtedly played a major role in the attempt to overthrow the dominant ideas in the field of Spanish psychiatry and displace its most influential figures. This article seeks to analyse the Conference's main organizational features and examine its most significant content, with the aim of evaluating its strategic importance in the context of both the psychiatrists' professional and scientific interests and their ideological and political concerns. Conference papers tackled issues such as neurology and psychiatry in wartime, vitamin deficiency and the nervous system, and new psychiatric treatments, including shock therapy. The Conference's marked ideological nature represented the beginning of a new professional dynamic, featuring the emergence or establishment of new leaders intent on laying the foundations of psychiatry during the early years of the Franco regime.

Method to determine the degrees of consistency in experimental datasets of perceptual color differences.

We propose a fuzzy method to analyze datasets of perceptual color differences with two main objectives: to detect inconsistencies between couples of color pairs and to assign a degree of consistency to each color pair in a dataset. This method can be thought as the outcome of a previous one developed for a similar purpose [J. Mod. Opt.56, 1447 (2009)JMOPEW0950-034010.1080/09500340902944038], whose performance is compared with the proposed one. In this work, we present the results achieved using the dataset employed to develop the current CIE/ISO color-difference formula, CIEDE2000, but the method could be applied to any dataset. Specifically, in the mentioned dataset, we find that some couples of color pairs have contradictory information, which can interfere in the successful development of future color-difference formulas as well as in checking the performance of current ones.

How color difference formulas depend on reference pairs in the underlying constant stimuli experiment.

For calculating color differences, the CIEDE2000 and CIE94 equations are widely used and recommended. These equations were derived more than a decade ago, based for a large part on the RIT-Dupont set of visual data. This data was collected from a series of psychophysical tests that use the method of constant stimuli. In this method, observers need to compare the color difference within a sample pair to that between a reference pair. In the current investigation, we show that the color difference equation significantly changes if reference pairs are chosen in the underlying visual experiments that differ from what was used when creating the RIT-Dupont dataset. The investigation is done using metallic paint samples representing two color centers, red and yellow-green. We show that the reproducibility differs for three different reference pairs, and that for modeling the visual data for the yellow-green color center, extra model terms are required as compared to the CIEDE2000 equation. Our results suggest that observers differ in their ability to mentally convert a color difference recognized in a sample pair into an equivalent color difference along the color difference direction represented by the reference pair. We also find that in these tests the tolerance to lightness differences is widened by a factor of 1.3 to 1.6, and that for the red color center the tolerance ellipsoid is rotated by 30° as compared to the CIEDE2000 equation. The latter observations are possibly due to the metallic texture in the samples used for the current experiment.

How psychophysical methods influence optimizations of color difference formulas.

For developing color difference formulas, there are several choices to be made on the psychophysical method used for gathering visual (observer) data. We tested three different psychophysical methods: gray scales, constant stimuli, and two-alternative forced choice (2AFC). Our results show that when using gray scales or constant stimuli, assessments of color differences are biased toward lightness differences. This bias is particularly strong in LCD monitor experiments, and also present when using physical paint samples. No such bias is found when using 2AFC. In that case, however, observer responses are affected by other factors that are not accounted for by current color difference formulas. For accurate prediction of relative color differences, our results show, in agreement with other works, that modern color difference formulas do not perform well. We also investigated if the use of digital images as presented on LCD displays is a good alternative to using physical samples. Our results indicate that there are systematic differences between these two media.

Subjectivity in clinical practice: on the origins of psychiatric semiology in early French alienism.

The aim of this article is to contribute to the analysis of the origins of psychiatric semiology, which by emphasizing subjectivity in clinical practice, gave birth to psychopathology as the scientific and intellectual enterprise of alienism. In other words, beyond simple anatomical and clinical observation, there was an effort to 'listen to' and 'read' the patient's delirium. In essence, the basic thesis which this short paper seeks to defend is that, despite a growing anatomical and clinical mind-set and a clear interest in physically locating mental illness within the body, during the Romantic period, psychiatry was able to construct a semiology largely based on the experience of the ego, on the inner world of the individual. This makes it possible to establish, from a clinical perspective, that the birth of alienism - of psychiatry - must be situated within the framework of a modernity in which the culture of subjectivity was one of its most characteristic features.

[Urban reform and social hygiene in Santiago de Chile. The liberal techno-utopianism of Benjamín Vicuña Mackenna (1872-1875)]. / Reforma urbana e higiene social en Santiago de Chile. La tecno-utopía liberal de Benjamín Vicuña Mackenna (1872-1875).

This paper analyzes the main features of the urban reforms by Benjamin Vicuña Mackenna in Santiago de Chile between 1872 and 1875. We pay special attention to the origin of the objectives of modernization, closely related to the political agenda of Latin American elites to create an urban culture (civilization). We also analyze the strategies of social defence that these reforms implied. The influence of French positivism and the Haussmann project in Paris was very important in the Vicuña Mackenna project and its model of a segregated city: the "European city" itself,--bourgeois, civilized and hygienic--, which should be protected, and the 'African township",--lower-class feral and unhygienic--, whose population must be regenerated and colonized.

Psychoanalysis and academia: the case of Angel Garma and the university of Buenos Aires.

The Spanish psychiatrist and psychoanalyst Ángel Garma-exiled in Argentina after the Spanish Civil War-was one of the founders and the first president of the Argentinian Psychoanalytical Association. Garma unsuccessfully tried to become a university lecturer on three occasions. His final attempt was in 1965, when he applied for a professorship in deep psychology at the Faculty of Philosophy and Literature of the University of Buenos Aires. The application he submitted for this professorship position has been located in Ángel Garma's personal archive. The aim of this article is to analyse this manuscript to search for clues about the author's relationship with his own work and to explain the priorities and interests he intended to explore in the university environment. The first part of the article analyses the content of his application for the professorship, contrasting this content with published work and reviewing the fundamental lines of Garma's psychoanalytical thought (child sexuality, psychoanalysis and psychosomatic medicine, the psychoanalytical institution, etc.). The second part suggests the main reasons why Garma failed in his attempts to become a university lecturer.

The reception of psychodrama in Spain: Correspondence between Jacob Levy Moreno and Ramón Sarró.

Jacob Levy Moreno, the well-known creator of psychodrama, had a close epistolary relationship with the Spanish psychiatrist Ramón Sarró; a collection of these letters has been located in the Sarró personal archive, deposited in the Library of Catalonia. After locating and arranging this correspondence, we proceeded to analyze and contextualize its contents. The analysis of this collection serves as a basis to outline the context in which the relationship between Moreno and Sarró developed, the role played by certain psychotherapy congresses in strengthening their relationships, and the process that resulted in the University of Barcelona awarding Moreno Doctor Honoris Causa. This study has allowed us to identify certain areas of how psychodrama was received in Spain during the 1960s and reflect on the creation of international collaboration networks and the creation of schools and professional and academic legitimation strategies in the wake of the approaches to group psychotherapy and psychodrama that Moreno developed while based in New York. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Generalization of color-difference formulas for any illuminant and any observer by assuming perfect color constancy in a color-vision model based on the OSA-UCS system.

The most widely used color-difference formulas are based on color-difference data obtained under D65 illumination or similar and for a 10° visual field; i.e., these formulas hold true for the CIE 1964 observer adapted to D65 illuminant. This work considers the psychometric color-vision model based on the Optical Society of America-Uniform Color Scales (OSA-UCS) system previously published by the first author [J. Opt. Soc. Am. A 21, 677 (2004); Color Res. Appl. 30, 31 (2005)] with the additional hypothesis that complete illuminant adaptation with perfect color constancy exists in the visual evaluation of color differences. In this way a computational procedure is defined for color conversion between different illuminant adaptations, which is an alternative to the current chromatic adaptation transforms. This color conversion allows the passage between different observers, e.g., CIE 1964 and CIE 1931. An application of this color conversion is here made in the color-difference evaluation for any observer and in any illuminant adaptation: these transformations convert tristimulus values related to any observer and illuminant adaptation to those related to the observer and illuminant adaptation of the definition of the color-difference formulas, i.e., to the CIE 1964 observer adapted to the D65 illuminant, and then the known color-difference formulas can be applied. The adaptations to the illuminants A, C, F11, D50, Planckian and daylight at any color temperature and for CIE 1931 and CIE 1964 observers are considered as examples, and all the corresponding transformations are given for practical use.

Alexandre Brierre de Boismont and the origins of the Spanish psychiatric profession.

This article examines the influence of the French alienist Alexandre Brierre de Boismont in the first development of the Spanish psychiatric profession during the third quarter of the 19th century. As an outstanding figure of French psychological medicine, Brierre enjoyed great scientific prestige among Spanish doctors, but he also took an active part in promoting and legitimizing the cause of alienism in Spain. For instance, he was involved in projects for the reform or creation of new mental hospitals, supported the admission of some Spanish colleagues into the Société Médico-Psychologique and made a decisive contribution to the social recognition of the professional and medico-legal expertise of alienists in Spain. His case is thus an excellent example of the important role played by international relations and the scientific and professional networks of European alienism in spreading the discourses and practices of the emerging psychological medicine.

Scaling of roughness and porosity in thin film deposition with mixed transport mechanisms and adsorption barriers.

Thin film deposition with particle transport mixing collimated and diffusive components and with barriers for adsorption are studied using numerical simulations and scaling approaches. Biased random walks on lattices are used to model the particle flux and the analogy with advective-diffusive transport is used to define a Peclet number P that represents the effect of the bias towards the substrate. An aggregation probability that relates the rates of adsorption and of the dominant transport mechanism plays the role of a Damkohler number D, where D≲1 is set to describe moderate to low adsorption rates. Very porous deposits with sparse branches are obtained with P≪1, whereas low porosity deposits with large height fluctuations at short scales are obtained with P≫1. For P≳1 in which the field bias is intense, an initial random deposition is followed by Kardar-Parisi-Zhang (KPZ) roughening. As the transport is displaced from those limiting conditions, the interplay of the transport and adsorption mechanisms establishes a condition to produce films with the smoothest surfaces for a constant deposited mass: with low adsorption barriers, a balance of random and collimated flux is required, whereas for high barriers the smoothest surfaces are obtained with P∼D^{1/2}. For intense bias, the roughness is shown to be a power law of P/D, whose exponent depends on the growth exponent ß of the KPZ class, and the porosity has a superuniversal scaling as (P/D)^{-1/3}. We also study a generalized ballistic deposition model with slippery particle aggregation that shows the universality of these relations in growth with dominant collimated flux, particle adsorption at any point of the deposit, and negligible adsorbate diffusion, in contrast with the models where aggregation is restricted to the outer surface.

Public health and nutrition after the Spanish Civil War. An intervention by the Rockefeller Foundation.

We describe a nutritional intervention by the Rockefeller Foundation's International Health Division in Spain after the Spanish Civil War, delineating the relationships between the technicians sent by the Rockefeller Foundation and the Spanish health authorities. We analyze reports of the nutritional situation in Spain in the early 1940s and the design and outcomes of a nutrition survey conducted in a district of Madrid by American and Spanish nutritionists. This nutritional survey, which was based on food intake interviews and was complemented with anthropometric measurements, clinical examinations, and blood tests, found several symptoms and signs of malnutrition. The Rockefeller Foundation's nutritional research was an important historical precedent for later studies made in emergency situations or armed conflicts. Similar surveys have been carried out in the last several decades by distinguished academic departments of public health and epidemiology and by humanitarian aid agencies.

Clinical profile of women diagnosed with Fabry disease non receiving enzyme replacement therapy.

INTRODUCTION AND OBJECTIVE: Fabry disease (FD) is an X-linked lysosomal storage disorder due to a deficiency of the α-galactosidase A enzyme. Although women were historically considered only carriers, many studies have contradicted this fact. The main aim of this work was to set the first Spanish study out of the on-going registries on health status and management of women diagnosed with FD who were not receiving enzyme replacement therapy (ERT). MATERIAL AND METHODS: An epidemiological, cross-sectional, descriptive and multicentre study was assessed in women diagnosed for FD who were not receiving ERT. Assessments on symptomatology and severity were collected using several clinical questionnaires. Additionally, clinical information and lab tests were obtained from clinical records. RESULTS: Thirty-three women with a mean age of 45.6±16.2 years were studied. Symptom onset was at a median age of 35.5 years old (range: 30.0-51.5), being diagnosed a median of 2 years later (range: 1.0-1.5). Missense mutations were the most prevalent mutation (n=22, 68.8%). Although 69% considered themselves as asymptomatic, 22 (66.7%) showed at least one FD-related clinical symptom. Using Mainz Severity Score index and Fabry International Prognosis Index neurological symptomatology obtained higher scores both for severity and prognostic. The EQ-5D questionnaire showed 42.2% patients referring to some anxiety or depression, and 30.3% thought that their life was somehow altered by the pain. 62.5% were not receiving any treatment and ERT was offered only to one patient (3.6%) who refused it. CONCLUSIONS: Although most of the heterozygous women for FD had not received ERT or either symptomatic treatment, they present symptoms of disease. Careful follow-up of female patients or some adjuvant treatment may be considered to delay progressive organ damage and improve patient quality of life.

Characterization of the human iris spectral reflectance with a multispectral imaging system.

We present a multispectral system developed and optimized for measurement of the spectral reflectance and the color of the human iris. We tested several sets of filters as acquisition channels, analyzed different reconstruction algorithms, and used different samples as training sets. The results obtained show that a conventional three-channel color camera (RGB) was enough to reconstruct the analyzed reflectances with high accuracy, obtaining averaged color differences of around 2-3 CIEDE2000 units and root mean square errors of around 0.01. The device developed was used to characterize 100 real irises corresponding to 50 subjects, 68 prostheses used in clinical practice, and 17 cosmetic colored contact lenses.