Detalhe da pesquisa
1.
LEGACY: Phase 2a Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of the Anti-EL (Endothelial Lipase) Antibody MEDI5884 in Patients With Stable Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
; 41(12): 3005-3014, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34706556
2.
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.
Crit Rev Toxicol
; 44(1): 1-49, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24180432
3.
Pancreatic safety of incretin-based drugs--FDA and EMA assessment.
N Engl J Med
; 370(9): 794-7, 2014 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24571751
4.
Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial.
Sci Transl Med
; 13(590)2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33883272
5.
Camptothecin induces the ubiquitin-like protein, ISG15, and enhances ISG15 conjugation in response to interferon.
J Interferon Cytokine Res
; 24(11): 647-54, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15684817
6.
Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
J Cell Physiol
; 194(3): 289-302, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12548549