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1.
Surg Laparosc Endosc Percutan Tech ; 27(3): e40-e43, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28582379

RESUMO

Vascularized lymph node transfers have multiple donor sites with risk of iatrogenic lymphedema. We sought to describe in detail a surgical technique that is safe, reproducible, and efficient in harvesting gastroepiploic vascularized lymph nodes using real-time indocyanine green (ICG) fluorescent imaging. Photographs and video were acquired from a case to depict a step-by-step approach. ICG was endoscopically injected into the submucosa of the greater curvature of the stomach at the outset of the procedure. A laparoscopic harvest of the gastroepiploic vascular pedicle and lymph nodes ensued with the assistance of fluorescent imaging. Laparoscopic gastroepiploic lymph node harvesting aided by real-time ICG fluorescent mapping technique is safe, feasible, and effective at gathering vascularized lymphatic tissue for successful lymph node transfer in patients with severe lymphedema.


Assuntos
Laparoscopia/métodos , Linfonodos/cirurgia , Linfedema/cirurgia , Coleta de Tecidos e Órgãos/métodos , Corantes , Endoscopia Gastrointestinal/métodos , Estudos de Viabilidade , Mucosa Gástrica/cirurgia , Humanos , Verde de Indocianina , Pessoa de Meia-Idade , Cuidados Pós-Operatórios , Estômago/cirurgia , Sítio Doador de Transplante
2.
J Gastrointest Surg ; 17(5): 847-56; discussion 856-7, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23435738

RESUMO

INTRODUCTION: Hereditary pancreatitis is a rare cause of chronic pancreatitis. In recent years, genetic mutations have been characterized. The rarity of this disorder has resulted in a gap in clinical knowledge. The aims were to characterize patients with hereditary pancreatitis and establish clinical guidelines. METHODS: Pediatric and adult endoscopic, surgical, radiologic, and genetic databases from 1998 to 2012 were searched. Patients with recurrent acute or chronic pancreatitis and genetic mutation for either PRSS-1, SPINK-1, or CFTR or those who met the family history criteria were included. Patients with pancreatitis due to other causes, without a positive family history, familial pancreatic cancer, or cystic fibrosis, were excluded. RESULTS: Eighty-seven patients were identified. Genetic testing confirmed the diagnosis in 54 patients (62 %). Eighty-five patients (98 %) underwent 263 endoscopic procedures including sphincterotomy (72 %), stone removal (49 %), and pancreatic duct stenting (82 %). Twenty-eight patients (32 %) have undergone 37 operations which included 19 resections and 18 drainage procedures. The interval between procedures for recurrent pain was longer for surgery than for endoscopic therapy (9.1 vs. 3.4 years, p < 0.05). CONCLUSIONS: Most children and young adults with hereditary pancreatitis can be managed initially with endoscopic therapy. When surgery is undertaken, the procedure should be tailored to the pancreatic anatomy and cancer risk.


Assuntos
Endoscopia/métodos , Pancreatite/genética , Pancreatite/cirurgia , Adolescente , Adulto , Proteínas de Transporte/genética , Criança , Pré-Escolar , Colangiopancreatografia Retrógrada Endoscópica , Regulador de Condutância Transmembrana em Fibrose Cística/genética , Drenagem , Endossonografia , Testes Genéticos , Humanos , Lactente , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade , Mutação , Neoplasias Pancreáticas/diagnóstico , Pancreatite/diagnóstico , Pancreatite/epidemiologia , Guias de Prática Clínica como Assunto , Recidiva , Estudos Retrospectivos , Estatísticas não Paramétricas , Stents , Tomografia Computadorizada por Raios X , Tripsina/genética , Inibidor da Tripsina Pancreática de Kazal , Estados Unidos/epidemiologia
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