Detalhe da pesquisa
1.
Sodium-Glucose Cotransporter Type 2 (SGLT-2) Inhibitors and Ketogenesis: the Good and the Bad.
Curr Diab Rep
; 20(12): 74, 2020 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33230620
2.
Navigating the "MACE" in Cardiovascular Outcomes Trials and decoding the relevance of Atherosclerotic Cardiovascular Disease benefits versus Heart Failure benefits.
Diabetes Obes Metab
; 21(8): 1780-1789, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30957945
3.
4.
Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes.
Nature
; 437(7058): 569-73, 2005 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-16177793
5.
SGLT2 Inhibitor-Induced Low-Grade Ketonemia Ameliorates Retinal Hypoxia in Diabetic Retinopathy-A Novel Hypothesis.
J Clin Endocrinol Metab
; 106(5): 1235-1244, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512450
6.
Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.
Mol Cell Biol
; 22(17): 6272-85, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12167719
7.
beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1.
Mol Cell Biol
; 24(20): 8929-37, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15456867
8.
G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes.
Mol Endocrinol
; 19(11): 2760-8, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15994203
9.
Current recommendations for prevention of cardiovascular disease in patients with diabetes mellitus. Part II of II.
Prev Cardiol
; 6(1): 34-7, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12624560
10.
Molecular mechanisms of diabetic cardiovascular disease.
Prev Cardiol
; 5(4): 183-7, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12417827
11.
Regulation of receptor tyrosine kinase signaling by GRKs and beta-arrestins.
Annu Rev Physiol
; 69: 561-77, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17002595
12.
Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors.
J Biol Chem
; 280(2): 1016-23, 2005 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15520010
13.
Beta -Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of beta 2 adrenergic receptor Galpha s signaling in 3T3-L1 adipocytes.
Proc Natl Acad Sci U S A
; 100(1): 161-6, 2003 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12509508
14.
GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation.
EMBO J
; 23(14): 2821-9, 2004 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15241473