Detalhe da pesquisa
1.
p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation.
Mol Cell
; 45(6): 719-30, 2012 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342344
2.
Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity.
J Biol Chem
; 292(13): 5405-5417, 2017 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188292
3.
Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation.
Mol Cell
; 34(4): 461-72, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19481526
4.
Addition of Navitoclax to Ongoing Ruxolitinib Therapy for Patients With Myelofibrosis With Progression or Suboptimal Response: Phase II Safety and Efficacy.
J Clin Oncol
; 40(15): 1671-1680, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35180010
5.
Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.
Mol Cell Biol
; 27(17): 6012-25, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17562858
6.
IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway.
Mol Cell Biol
; 27(21): 7451-61, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17709380
7.
Development of an intracellularly acting inhibitory peptide selective for PKN.
Biochem J
; 425(2): 445-53, 2009 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19857203
8.
Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.
Biochem J
; 424(1): 47-60, 2009 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19740074
9.
VHL Synthetic Lethality Signatures Uncovered by Genotype-Specific CRISPR-Cas9 Screens.
CRISPR J
; 2: 230-245, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31436504
10.
First-in-Human Study of Mivebresib (ABBV-075), an Oral Pan-Inhibitor of Bromodomain and Extra Terminal Proteins, in Patients with Relapsed/Refractory Solid Tumors.
Clin Cancer Res
; 25(21): 6309-6319, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31420359
11.
Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315.
J Med Chem
; 61(15): 6647-6657, 2018 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30004704
12.
Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε.
PLoS One
; 7(7): e41494, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22859992
13.
Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation.
Cancer Res
; 72(13): 3260-9, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22552288
14.
IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.
Mol Cell Biol
; 32(13): 2479-89, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22547678
15.
Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis.
Mol Cell
; 25(5): 689-702, 2007 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17349956
16.
Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates.
Nat Protoc
; 1(1): 375-9, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17406259
17.
Building a human kinase gene repository: bioinformatics, molecular cloning, and functional validation.
Proc Natl Acad Sci U S A
; 102(23): 8114-9, 2005 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15928075
18.
A rapid method for determining protein kinase phosphorylation specificity.
Nat Methods
; 1(1): 27-9, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15782149