Detalhe da pesquisa
1.
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.
Cell
; 150(3): 533-48, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863007
2.
Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice.
Nucleic Acids Res
; 50(20): 11401-11414, 2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944903
3.
Correction of cilia structure and function alleviates multi-organ pathology in Bardet-Biedl syndrome mice.
Hum Mol Genet
; 29(15): 2508-2522, 2020 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32620959
4.
Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.
Am J Physiol Renal Physiol
; 315(1): F57-F73, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29537311
5.
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Hum Mol Genet
; 25(11): 2245-2255, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27053712
6.
CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis.
Am J Physiol Renal Physiol
; 310(11): F1414-22, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27076647
7.
Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease.
Hum Mol Genet
; 21(15): 3397-407, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563011
8.
Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.
Nature
; 444(7121): 949-52, 2006 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17122773
9.
Glucosylceramide synthase inhibition protects against cardiac hypertrophy in chronic kidney disease.
Sci Rep
; 12(1): 9340, 2022 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35660779
10.
Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models.
Cells
; 11(4)2022 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35203245
11.
Inhibition of TGF-ß Increases Bone Volume and Strength in a Mouse Model of Osteogenesis Imperfecta.
JBMR Plus
; 5(9): e10530, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34532615
12.
Glycosphingolipid metabolism and polycystic kidney disease.
Cell Signal
; 69: 109526, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31911181
13.
Dysregulated Expression of microRNA-21 and Disease-Related Genes in Human Patients and in a Mouse Model of Alport Syndrome.
Hum Gene Ther
; 30(7): 865-881, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30808234
14.
Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus.
J Clin Invest
; 114(10): 1433-43, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15545994
15.
In vitro cystogenesis: the search for drugs antagonizing cyst development.
Nephrol Ther
; 2 Suppl 2: S109-14, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17373209
16.
Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD.
Physiol Rep
; 4(12)2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27356569
17.
Cation channel regulation by COOH-terminal cytoplasmic tail of polycystin-1: mutational and functional analysis.
Physiol Genomics
; 8(2): 87-98, 2002 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-11875186
18.
CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD.
Cell Cycle
; 11(21): 4040-6, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23032260
19.
mTOR signaling in polycystic kidney disease.
Trends Mol Med
; 17(11): 625-33, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21775207
20.
Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.
Nat Med
; 16(7): 788-92, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20562878