Detalhe da pesquisa
1.
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Nature
; 623(7989): 1079-1085, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938782
2.
Adaptive immunity induces mutualism between commensal eukaryotes.
Nature
; 596(7870): 114-118, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34262174
3.
Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection.
PLoS Pathog
; 19(8): e1011579, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37611070
4.
Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis.
PLoS Biol
; 20(8): e3001762, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35976859
5.
Efficacy of an oral lipid nanocrystal formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis.
Antimicrob Agents Chemother
; : e0154023, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687015
6.
Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B.
Antimicrob Agents Chemother
; 68(5): e0154523, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557112
7.
Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells.
PLoS Pathog
; 18(7): e1010681, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35797411
8.
COVID-19 Associated Rhino-Orbital-Cerebral Mucormycosis: Clinical Features, Antifungal Susceptibility, Management and Outcome in a Tertiary Hospital in Iran.
Mycopathologia
; 188(5): 783-792, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37672164
9.
The Combination Treatment of Fosmanogepix and Liposomal Amphotericin B Is Superior to Monotherapy in Treating Experimental Invasive Mold Infections.
Antimicrob Agents Chemother
; 66(7): e0038022, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35670592
10.
Manogepix, the Active Moiety of the Investigational Agent Fosmanogepix, Demonstrates In Vitro Activity against Members of the Fusarium oxysporum and Fusarium solani Species Complexes.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33722886
11.
Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis.
J Antimicrob Chemother
; 76(10): 2636-2639, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34263306
12.
The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection.
PLoS Pathog
; 15(8): e1007460, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381597
13.
Selective inhibition of Rhizopus eumelanin biosynthesis by novel natural product scaffold-based designs caused significant inhibition of fungal pathogenesis.
Biochem J
; 477(13): 2489-2507, 2020 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32538426
14.
Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31818813
15.
Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32205345
16.
Preserving Vascular Integrity Protects Mice against Multidrug-Resistant Gram-Negative Bacterial Infection.
Antimicrob Agents Chemother
; 64(8)2020 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393494
17.
The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection.
PLoS Pathog
; 14(5): e1007056, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29746596
18.
Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685475
19.
APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis.
Antimicrob Agents Chemother
; 63(2)2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455236
20.
Metabolic Profiling of Candida auris, a Newly-Emerging Multi-Drug Resistant Candida Species, by GC-MS.
Molecules
; 24(3)2019 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678308