Detalhe da pesquisa
1.
Allopurinol and oxypurinol differ in their strength and mechanisms of inhibition of xanthine oxidoreductase.
J Biol Chem
; 299(9): 105189, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37625592
2.
Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations.
Pflugers Arch
; 475(4): 489-504, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749388
3.
Urate Transporter ABCG2 Function and Asymptomatic Hyperuricemia: A Retrospective Cohort Study of CKD Progression.
Am J Kidney Dis
; 81(2): 134-144.e1, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35810827
4.
Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.
Proc Natl Acad Sci U S A
; 117(31): 18175-18177, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690690
5.
Genome-wide meta-analysis between renal overload type and renal underexcretion type of clinically defined gout in Japanese populations.
Mol Genet Metab
; 136(3): 186-189, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35148957
6.
Genetic epidemiological analysis of hypouricaemia from 4993 Japanese on non-functional variants of URAT1/SLC22A12 gene.
Rheumatology (Oxford)
; 61(3): 1276-1281, 2022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34255816
7.
Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12.
Rheumatology (Oxford)
; 60(11): 5224-5232, 2021 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33821957
8.
Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study.
BMC Nephrol
; 22(1): 207, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34078313
9.
Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients.
Ann Rheum Dis
; 79(5): 657-665, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32238385
10.
Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.
Ann Rheum Dis
; 78(10): 1430-1437, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31289104
11.
The Persistent Generalized Muscle Contraction in Siblings with Molybdenum Cofactor Deficiency Type A.
Neuropediatrics
; 50(2): 126-129, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30695801
12.
Urate Transport via Paracellular Route across Epithelial Cells.
Biol Pharm Bull
; 42(1): 43-49, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30606989
13.
Diet-induced hyperhomocysteinemia impairs vasodilation in 5/6-nephrectomized rats.
Amino Acids
; 50(10): 1485-1494, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30062489
14.
GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.
Ann Rheum Dis
; 76(5): 869-877, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899376
15.
Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.
Ann Rheum Dis
; 75(4): 652-9, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25646370
16.
First clinical practice guideline for renal hypouricaemia: a rare disorder that aided the development of urate-lowering drugs for gout.
Rheumatology (Oxford)
; 60(9): 3961-3963, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34469572
17.
Functional analysis of novel allelic variants in URAT1 and GLUT9 causing renal hypouricemia type 1 and 2.
Clin Exp Nephrol
; 20(4): 578-584, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26500098
18.
Rare case of nephrocalcinosis in the distal tubules caused by hereditary renal hypouricaemia 3 months after kidney transplantation.
Nephrology (Carlton)
; 21 Suppl 1: 67-71, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26971588
19.
Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels.
Ann Rheum Dis
; 79(1): 164-166, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31780526
20.
Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia.
Circ J
; 79(5): 1125-32, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25739858