Detalhe da pesquisa
1.
Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol.
J Biol Chem
; 290(8): 4573-4589, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25552479
2.
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.
J Med Chem
; 64(1): 417-429, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378180
3.
Tandem intramolecular photocycloaddition-retro-Mannich fragmentation as a route to spiro[pyrrolidine-3,3'-oxindoles]. Total synthesis of (+/-)-coerulescine, (+/-)-horsfiline, (+/-)-elacomine, and (+/-)-6-deoxyelacomine.
J Org Chem
; 75(11): 3569-77, 2010 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20429523
4.
1-Benzylbenzimidazoles: the discovery of a novel series of bradykinin B(1) receptor antagonists.
Bioorg Med Chem Lett
; 18(18): 5027-31, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18752949
5.
Tandem photocycloaddition-retro-mannich fragmentation of enaminones. A route to spiropyrrolines and the tetracyclic core of koumine.
Org Lett
; 8(6): 1081-4, 2006 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16524273