Detalhe da pesquisa
1.
Rapid initiation of cell cycle reentry processes protects neurons from amyloid-ß toxicity.
Proc Natl Acad Sci U S A
; 118(12)2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737393
2.
Role of monomeric amyloid-ß in cognitive performance in Alzheimer's disease: Insights from clinical trials with secretase inhibitors and monoclonal antibodies.
Pharmacol Res
; 187: 106631, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36586644
3.
Syntaxins 6 and 8 facilitate tau into secretory pathways.
Biochem J
; 478(7): 1471-1484, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33769438
4.
A critical appraisal of tau-targeting therapies for primary and secondary tauopathies.
Alzheimers Dement
; 18(5): 1008-1037, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34533272
5.
Carnosine modulates the Sp1-Slc31a1/Ctr1 copper-sensing system and influences copper homeostasis in murine CNS-derived cells.
Am J Physiol Cell Physiol
; 316(2): C235-C245, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30485136
6.
Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
Am J Pathol
; 188(6): 1447-1456, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29577934
7.
Responsiveness of Carnosine Homeostasis Genes in the Pancreas and Brain of Streptozotocin-Treated Mice Exposed to Dietary Carnosine.
Int J Mol Sci
; 19(6)2018 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29890740
8.
Should we lower or raise levels of amyloid-ß in the brains of Alzheimer patients?
Pharmacol Res
; 183: 106390, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35940397
9.
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Acta Neuropathol
; 130(5): 661-78, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437864
10.
Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Neuron
; 112(8): 1249-1264.e8, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366598
11.
Accelerating Alzheimer's disease drug discovery and development: what's the way forward?
Expert Opin Drug Discov
; 16(7): 727-735, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33653187
12.
History of Extensive Disease Small Cell Lung Cancer Treatment: Time to Raise the Bar? A Review of the Literature.
Cancers (Basel)
; 13(5)2021 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33673630
13.
Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology.
Sci Rep
; 11(1): 9616, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33953334
14.
Intratumoral Cellular Heterogeneity: Implications for Drug Resistance in Patients with Non-Small Cell Lung Cancer.
Cancers (Basel)
; 13(9)2021 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33922215
15.
Synthesis and Characterization of Novel Mono- and Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult.
J Med Chem
; 64(12): 8333-8353, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097384
16.
Should drug discovery scientists still embrace the amyloid hypothesis for Alzheimer's disease or should they be looking elsewhere?
Expert Opin Drug Discov
; 15(11): 1241-1251, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32686970
17.
Perspective: Is therapeutic plasma exchange a viable option for treating Alzheimer's disease?
Alzheimers Dement (N Y)
; 6(1): e12004, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32211508
18.
Next Generation Sequencing in Non-Small Cell Lung Cancer: Pitfalls and Opportunities.
Diagnostics (Basel)
; 10(12)2020 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33333743
19.
Initial failures of anti-tau antibodies in Alzheimer's disease are reminiscent of the amyloid-ß story.
Neural Regen Res
; 18(1): 117-118, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35799522
20.
No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice.
PLoS One
; 11(10): e0163236, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27736877