Detalhe da pesquisa
1.
Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages.
Nat Immunol
; 16(7): 746-54, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26030024
2.
Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53.
Proc Natl Acad Sci U S A
; 121(12): e2315248121, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38483995
3.
DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation.
EMBO Rep
; 24(5): e55543, 2023 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36880575
4.
Differences in H3K4me3 and chromatin accessibility contribute to altered T-cell receptor signaling in neonatal naïve CD4 T cells.
Immunol Cell Biol
; 100(7): 562-579, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35608955
5.
iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Proc Natl Acad Sci U S A
; 112(19): 6080-5, 2015 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25918388
6.
iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Eur J Immunol
; 46(12): 2737-2748, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27601030
7.
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Proc Natl Acad Sci U S A
; 110(28): 11433-8, 2013 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23801765
8.
FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways.
Clin Transl Med
; 13(5): e1223, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37165578
9.
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.
J Cell Sci
; 123(Pt 22): 3913-22, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20980382
10.
CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.
Nat Commun
; 13(1): 1477, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304452
11.
Resveratrol attenuates C5a-induced inflammatory responses in vitro and in vivo by inhibiting phospholipase D and sphingosine kinase activities.
FASEB J
; 23(8): 2412-24, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19346296
12.
The Role of iRhom2 in Metabolic and Cardiovascular-Related Disorders.
Front Cardiovasc Med
; 7: 612808, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33330676
13.
The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner.
Front Cell Infect Microbiol
; 10: 620392, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33585287
14.
A Pathophysiological Perspective on COVID-19's Lethal Complication: From Viremia to Hypersensitivity Pneumonitis-like Immune Dysregulation.
Infect Chemother
; 52(3): 335-344, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32537960
15.
Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation.
Metabolism
; 106: 154194, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32135161
16.
Novel functions of inactive rhomboid proteins in immunity and disease.
J Leukoc Biol
; 106(4): 823-835, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31369701
17.
Loss of RHBDF2 results in an early-onset spontaneous murine colitis.
J Leukoc Biol
; 105(4): 767-781, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30694569
18.
Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.
Nat Commun
; 9(1): 3594, 2018 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185805
19.
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
J Clin Invest
; 128(4): 1397-1412, 2018 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29369823
20.
Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice.
Front Immunol
; 8: 291, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28382035