1.
Org Lett
; 7(6): 1101-3, 2005 Mar 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15760149
RESUMO
[reaction: see text] Peptides containing a secondary amine and a carboxylic acid in a specific orientation to each other are presented as highly efficient catalysts for asymmetric aldol reactions: (1) their activity is considerably higher compared to that of proline, and (2) the enantioselectivity of the peptidic catalysts can be changed from (R)- to (S)-selectivity by simple modifications of the secondary structure.
Assuntos
Aldeídos/química , Aminas/química , Peptídeos/química , Catálise , Estrutura Molecular , Prolina/química , Estereoisomerismo , Relação Estrutura-Atividade
2.
Chemphyschem
; 3(10): 881-5, 2002 Oct 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12465187