Detalhe da pesquisa
1.
Design, synthesis, and biological evaluation of novel somatostatin receptor subtype-2 agonists: Optimization for potency and risk mitigation of hERG and phospholipidosis.
Bioorg Med Chem
; 49: 116424, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34626901
2.
Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice.
Nat Med
; 10(11): 1208-15, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15489860
3.
Discovery and SAR Studies of Orally Active Somatostatin Receptor Subtype-2 (SSTR2) Agonists for the Treatment of Acromegaly.
ACS Chem Neurosci
; 11(10): 1482-1494, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315148
4.
Increased oxidative stress in obesity and its impact on metabolic syndrome.
J Clin Invest
; 114(12): 1752-61, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15599400
5.
Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors.
Diabetes
; 52(7): 1655-63, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12829629
6.
Sulfonylurea agents exhibit peroxisome proliferator-activated receptor gamma agonistic activity.
J Biol Chem
; 280(25): 23653-9, 2005 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15764598
7.
Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast.
Biochem Biophys Res Commun
; 331(2): 520-6, 2005 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15850790
8.
Intectin, a novel small intestine-specific glycosylphosphatidylinositol-anchored protein, accelerates apoptosis of intestinal epithelial cells.
J Biol Chem
; 279(41): 42867-74, 2004 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-15292182