Detalhe da pesquisa
1.
Protein kinase C targeting of luminal (T-47D), luminal/HER2-positive (BT474), and triple negative (HCC1806) breast cancer cells in-vitro with AEB071 (Sotrastaurin) is efficient but mediated by subtype specific molecular effects.
Arch Gynecol Obstet
; 306(4): 1197-1210, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298675
2.
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-ß.
Nature
; 485(7400): 651-5, 2012 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22660329
3.
Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration.
BMC Neurosci
; 14: 108, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24083638
4.
Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aß is induced by pyroglutamate-Aß formation.
J Neurosci
; 31(36): 12790-801, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21900558
5.
Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients.
Sci Rep
; 11(1): 6761, 2021 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33762647
6.
Cancer-associated cells release citrate to support tumour metastatic progression.
Life Sci Alliance
; 4(6)2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758075
7.
An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice.
J Clin Invest
; 117(11): 3540-50, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17965774
8.
Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.
J Neurochem
; 106(3): 1225-36, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18627432
9.
Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer Development In Vivo.
Cancer Res
; 78(10): 2513-2523, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510993
10.
Shift in prevalence of HPV types in cervical cytology specimens in the era of HPV vaccination.
Oncol Lett
; 12(1): 601-610, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27347187
11.
Cell type specific expression of secretory TFF peptides: colocalization with mucins and synthesis in the brain.
Int Rev Cytol
; 213: 147-81, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-11837892
12.
A luminous efficiency function, V*(lambda), for daylight adaptation.
J Vis
; 5(11): 948-68, 2005 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16441195
13.
A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.
Endocrinology
; 145(5): 2531-41, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-14726450
14.
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.
EMBO Mol Med
; 3(9): 545-58, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21774078
15.
Ocular TFF-peptides: new mucus-associated secretory products of conjunctival goblet cells.
Adv Exp Med Biol
; 506(Pt A): 313-6, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12613926
16.
Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology.
Nat Med
; 14(10): 1106-11, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18836460
17.
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration.
Am J Physiol Gastrointest Liver Physiol
; 290(4): G827-38, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16537974
18.
Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry.
Immunity
; 22(4): 451-65, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15845450
19.
The molecular basis of dichromatic color vision in males with multiple red and green visual pigment genes.
Hum Mol Genet
; 11(1): 23-32, 2002 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11772996
20.
Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase.
Genes Dev
; 18(5): 486-91, 2004 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15014044