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1.
B-ENT ; 10(4): 299-302, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25654954

RESUMO

OBJECTIVES: To describe an extremely rare pediatric sinonasal schwannoma, and to reviewmanagement strategies and relevant literature. METHODS: Case report of pediatric sinonasal schwannoma, that was imaged with computed tomography and magnetic resonance imaging and managed endoscopically. Immunohistochemical analysis was performed to determine pathology. RESULTS: A 12-year-old girl presented with a 2-month history of progressive left exophthalmos. Imaging studies showed a large heterogeneous tumour arising from the ethmoid sinus and extending to the base of the skull and to the orbital cavity. The lesion was removed with an endonasal radical excision. The final pathological diagnosis was schwannoma. There was no tumour recurrence or any major complication during the 2-year follow up. CONCLUSION: Schwannoma should be considered in the differential diagnosis for pediatric patients with intranasal masses. Depending on the location and extent of the tumour, endonasal endoscopic excision could be a suitable management strategy.


Assuntos
Endoscopia/métodos , Seio Etmoidal/cirurgia , Neurilemoma/cirurgia , Órbita/cirurgia , Neoplasias dos Seios Paranasais/cirurgia , Base do Crânio/cirurgia , Criança , Seio Etmoidal/diagnóstico por imagem , Seio Etmoidal/patologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Neurilemoma/diagnóstico por imagem , Neurilemoma/patologia , Órbita/diagnóstico por imagem , Neoplasias dos Seios Paranasais/diagnóstico por imagem , Neoplasias dos Seios Paranasais/patologia , Base do Crânio/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Resultado do Tratamento
2.
J Microbiol Immunol Infect ; 34(4): 297-300, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11825012

RESUMO

Cytomegalovirus causes pneumonia, hepatitis, thrombocytopenia, and hemolytic anemia. Cytomegalovirus adrenalitis in premature infants, however, is rare. This report described a premature newborn who had progressively worsening hyperbilirubinemia, pancytopenia, and hepatosplenomegaly at the age of 4 days. The baby's mother had prolonged rupture of amniotic membrane for about 8 weeks. The infant received exchange blood transfusion, empiric antibiotics treatment, and mechanical ventilation. Pneumonia and sepsis developed at the age of 18 days. Serum anticytomegalovirus immunoglobulin M and urine virus culture were positive for cytomegalovirus. The baby died at the age of 22 days. Autopsy showed cytomegalovirus infection complicated with interstitial pneumonitis and pulmonary edema, subacute bronchopulmonary dysplasia with interstitial fibrosis, and adrenalitis. We concluded that the functional status of the adrenal glands in cytomegalovirus-infected premature newborns who have unexplained electrolytes imbalance, fever, diarrhea, weight loss, or hypotension should be closely followed because of the possible involvement of adrenal glands.


Assuntos
Doenças das Glândulas Suprarrenais/microbiologia , Infecções por Citomegalovirus/congênito , Doenças das Glândulas Suprarrenais/congênito , Doenças das Glândulas Suprarrenais/patologia , Evolução Fatal , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Inflamação/microbiologia , Pneumonia/complicações , Pneumonia/microbiologia
3.
Transplant Proc ; 35(8): 2888-90, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14697929

RESUMO

A young adult was diagnosed with steroid-resistant minimal change disease (MCD) without evidence of focal segmental glomerulosclerosis (FSGS) despite serial and detailed sectioning and screening of the renal biopsy. He received initial treatment with steroids and then cyclosporine plus low-dose steroids for 2 years. Renal function progressively deteriorated due to resistance to steroid and cyclosporine. Two months after initiation of hemodialysis, the patient received a living-related allogenic kidney transplant. However, recurrent nephrotic syndrome and renal insufficiency occurred after transplantation. In spite of aggressive treatment, renal function showed no significant improvement. The kidney graft was removed 2 weeks after transplantation. Serial sectioning and thorough sampling and screening revealed no evidence of FSGS, but light microscopy and electron microscopy showed the typical morphologic pattern of MCD, corresponding to the pretransplant diagnosis. We believe that this is the first reported case of recurrent MCD after renal transplant.


Assuntos
Glomerulosclerose Segmentar e Focal/cirurgia , Transplante de Rim/patologia , Adulto , Glomerulosclerose Segmentar e Focal/imunologia , Glomerulosclerose Segmentar e Focal/patologia , Humanos , Imunoglobulina A/sangue , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Glomérulos Renais/ultraestrutura , Transplante de Rim/imunologia , Masculino , Microscopia Eletrônica , Recidiva , Diálise Renal , Resultado do Tratamento
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