Detalhe da pesquisa
1.
APC/PIK3CA mutations and ß-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells.
Br J Cancer
; 130(1): 151-162, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37968472
2.
c-KIT regulates stability of cancer stemness in CD44-positive colorectal cancer cells.
Biochem Biophys Res Commun
; 527(4): 1014-1020, 2020 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32439168
3.
Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo.
Sci Rep
; 11(1): 15125, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34302038
4.
Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase.
Mol Cancer Ther
; 19(3): 765-776, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31907221
5.
Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer.
J Med Chem
; 63(8): 4183-4204, 2020 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202790
6.
mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
Oncotarget
; 8(29): 47902-47915, 2017 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28615517