Detalhe da pesquisa
1.
Establishment of a t(11;19), KMT2A Rearranged B-ALL Cell Line for Preclinical Evaluation and Novel Therapeutics Development for Refractory Infant Leukemia.
J Pediatr Hematol Oncol
; 45(6): e750-e756, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37494611
2.
Targeted Polo-like Kinase Inhibition Combined With Aurora Kinase Inhibition in Pediatric Acute Leukemia Cells.
J Pediatr Hematol Oncol
; 41(6): e359-e370, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30702467
3.
Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.
Stem Cells
; 30(6): 1064-75, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22415968
4.
Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion.
J Exp Clin Cancer Res
; 42(1): 175, 2023 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37464364
5.
Ion channels in pediatric CNS Atypical Teratoid/Rhabdoid Tumor (AT/RT) cells: potential targets for novel therapeutic agents.
J Neurooncol
; 107(1): 111-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21971736
6.
The T-type Calcium Channel Cav3.1 in Y79 Retinoblastoma Cells is Regulated by the Epidermal Growth Factor Receptor via the MAPK Signaling Pathway.
Curr Eye Res
; 47(3): 426-435, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34674590
7.
Curcumin blocks Kv11.1 (erg) potassium current and slows proliferation in the infant acute monocytic leukemia cell line THP-1.
Cell Physiol Biochem
; 28(6): 1169-80, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22179005
8.
Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition.
Cancer Cell Int
; 11(1): 44, 2011 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22206574
9.
Cytotoxicity, drug combinability, and biological correlates of ABT-737 against acute lymphoblastic leukemia cells with MLL rearrangement.
Pediatr Blood Cancer
; 56(3): 353-60, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21225911
10.
Analysis of multiple growth regulatory proteins using dissociable staining antibody arrays on solid tumor biopsy specimens.
Fetal Pediatr Pathol
; 30(3): 177-88, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21355677
11.
Cytotoxicity and Target Modulation in Pediatric Solid Tumors by the Proteasome Inhibitor Carfilzomib.
Curr Cancer Drug Targets
; 21(9): 804-811, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33949932
12.
Human SNF5 arming of double-deleted vaccinia virus shows oncolytic and cytostatic activity against central nervous system atypical teratoid/rhabdoid tumor cells.
Cancer Gene Ther
; 28(7-8): 739-744, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32678303
13.
Childhood acute lymphoblastic leukemia (ALL) presenting with severe osteolysis: a model to study leukemia-bone interactions and potential targeted therapeutics.
Pediatr Hematol Oncol
; 27(3): 212-27, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20367265
14.
The dawn of targeted therapies for triple negative breast cancer (TNBC): a snapshot of investigational drugs in phase I and II trials.
Expert Opin Investig Drugs
; 29(11): 1199-1208, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32869671
15.
Effects of Hsp90 inhibition in neuroblastoma: analysis of drug sensitivity, target modulation and the influence of bone marrow microenvironment.
J Exp Ther Oncol
; 7(3): 183-93, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19066127
16.
Targeting the Proteasome in Refractory Pediatric Leukemia Cells: Characterization of Effective Cytotoxicity of Carfilzomib.
Target Oncol
; 13(6): 779-793, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446871
17.
In Vitro Sensitivity Profiling of Neuroblastoma Cells Against A Comprehensive Small Molecule Kinase Inhibitor Library to Identify Agents for Future Therapeutic Studies.
Curr Cancer Drug Targets
; 17(6): 569-584, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875952
18.
Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients.
Rheumatology (Oxford)
; 50(2): 417-9, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20693540
19.
RSK2: a promising therapeutic target for the treatment of triple-negative breast cancer.
Expert Opin Ther Targets
; 24(1): 1-5, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31875730
20.
Druggable targets in pediatric neurocutaneous melanocytosis: Molecular and drug sensitivity studies in xenograft and ex vivo tumor cell culture to identify agents for therapy.
Neuro Oncol
; 17(6): 822-31, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25395461