Detalhe da pesquisa
1.
Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication.
Mol Cell
; 37(1): 67-78, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20129056
2.
Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element.
Nucleic Acids Res
; 43(19): 9262-75, 2015 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26253742
3.
In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication.
PLoS Genet
; 10(12): e1004832, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25474639
4.
Subnormal levels of POLγA cause inefficient initiation of light-strand DNA synthesis and lead to mitochondrial DNA deletions and progressive external ophthalmoplegia [corrected].
Hum Mol Genet
; 22(12): 2411-22, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23446635
5.
TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication.
Hum Mol Genet
; 22(10): 1983-93, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393161
6.
The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis.
Nucleic Acids Res
; 39(21): 9238-49, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21840902
7.
MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation.
Cell Metab
; 17(4): 618-26, 2013 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562081