Detalhe da pesquisa
1.
cGAS goes viral: A conserved immune defense system from bacteria to humans.
Mol Cell
; 84(1): 120-130, 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38181755
2.
Ubiquitin-like conjugation by bacterial cGAS enhances anti-phage defence.
Nature
; 616(7956): 326-331, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36848932
3.
Peptide design by optimization on a data-parameterized protein interaction landscape.
Proc Natl Acad Sci U S A
; 115(44): E10342-E10351, 2018 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322927
4.
Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Proc Natl Acad Sci U S A
; 115(5): E886-E895, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29339518
5.
Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure
; 27(4): 606-617.e5, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773399
6.
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Elife
; 62017 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28594323