Detalhe da pesquisa
1.
Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokinetics.
Bioorg Med Chem
; 22(1): 447-58, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24275348
2.
Discovery of an irreversible HCV NS5B polymerase inhibitor.
Bioorg Med Chem Lett
; 23(24): 6585-7, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24252545
3.
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase.
Bioorg Med Chem
; 21(7): 2007-17, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23434368
4.
II. Novel HCV NS5B polymerase inhibitors: discovery of indole C2 acyl sulfonamides.
Bioorg Med Chem Lett
; 22(1): 713-7, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22104146
5.
I. Novel HCV NS5B polymerase inhibitors: discovery of indole 2-carboxylic acids with C3-heterocycles.
Bioorg Med Chem Lett
; 21(18): 5336-41, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21840715
6.
Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides.
Bioorg Med Chem Lett
; 20(7): 2119-24, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20219368
7.
Pyridine Carboxamides: Potent Palm Site Inhibitors of HCV NS5B Polymerase.
ACS Med Chem Lett
; 1(9): 466-71, 2010 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900232