Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 220
Filtrar
1.
Phys Rev Lett ; 132(3): 035101, 2024 Jan 19.
Artigo em Inglês | MEDLINE | ID: mdl-38307081

RESUMO

Magnetic reconnection is a ubiquitous and fundamental process in plasmas by which magnetic fields change their topology and release magnetic energy. Despite decades of research, the physics governing the reconnection process in many parameter regimes remains controversial. Contemporary reconnection theories predict that long, narrow current sheets are susceptible to the tearing instability and split into isolated magnetic islands (or plasmoids), resulting in an enhanced reconnection rate. While several experimental observations of plasmoids in the regime of low-to-intermediate ß (where ß is the ratio of plasma thermal pressure to magnetic pressure) have been made, there is a relative lack of experimental evidence for plasmoids in the high-ß reconnection environments which are typical in many space and astrophysical contexts. Here, we report strong experimental evidence for plasmoid formation in laser-driven high-ß reconnection experiments.

2.
Environ Sci Technol ; 50(22): 12232-12240, 2016 11 15.
Artigo em Inglês | MEDLINE | ID: mdl-27758097

RESUMO

Uranium groundwater contamination due to U mining and processing affects numerous sites globally. Bioreduction of soluble, mobile U(VI) to U(IV)-bearing solids is potentially a very effective remediation strategy. Uranium isotopes (238U/235U) have been utilized to track the progress of microbial reduction, with laboratory and field studies finding a ∼1‰ isotopic fractionation, with the U(IV) product enriched in 238U. However, the isotopic fractionation produced by adsorption may complicate the use of 238U/235U to trace microbial reduction. A previous study found that adsorption of U(VI) onto Mn oxides produced a -0.2‰ fractionation with the adsorbed U(VI) depleted in 238U. In this study, adsorption to quartz, goethite, birnessite, illite, and aquifer sediments induced an average isotopic fractionation of -0.15‰ with the adsorbed U(VI) isotopically lighter than coexisting aqueous U(VI). In bicarbonate-bearing matrices, the fractionation depended little on the nature of the sorbent, with only birnessite producing an atypically large fractionation. In the case of solutions with ionic strengths much lower than those of typical groundwater, less isotopic fractionation was produced than U(VI) solutions with greater ionic strength. Studies using U isotope data to assess U(VI) reduction must consider adsorption as a lesser, but significant isotope fractionation process.


Assuntos
Urânio , Poluentes Radioativos da Água , Adsorção , Sedimentos Geológicos , Água Subterrânea , Minerais
4.
Diabet Med ; 31(8): 927-35, 2014 08.
Artigo em Inglês | MEDLINE | ID: mdl-24698119

RESUMO

AIM: To determine whether using HbA1c for screening and management could be confounded by age differences, whether age effects can be explained by unrecognized diabetes and prediabetes, insulin resistance or postprandial hyperglycaemia, and whether the effects of aging have an impact on diagnostic accuracy. METHODS: We conducted a cross-sectional analysis in adults without known diabetes in the Screening for Impaired Glucose Tolerance (SIGT) study 2005-2008 (n=1573) and the National Health and Nutrition Examination Survey (NHANES) 2005-2006 (n=1184). RESULTS: Both glucose intolerance and HbA(1c) levels increased with age. In univariate analyses including all subjects, HbA(1c) levels increased by 0.93 mmol/mol (0.085%) per 10 years of age in the SIGT study and by 1.03 mmol/mol (0.094%) per 10 years in the NHANES; in both datasets, the HbA(1c) increase was 0.87 mmol/mol (0.08%) per 10 years in subjects without diabetes, and 0.76 mmol/mol (0.07%) per 10 years in subjects with normal glucose tolerance, all P<0.001. In multivariate analyses of subjects with normal glucose tolerance, the relationship between age and HbA(1c) remained significant (P<0.001) after adjustment for covariates including race, BMI, waist circumference, sagittal abdominal diameter, triglyceride/HDL ratio, and fasting and 2-h plasma glucose and other glucose levels, as assessed by an oral glucose tolerance test. In both datasets, the HbA(1c) of an 80-year-old individual with normal glucose tolerance would be 3.82 mmol/mol (0.35%) greater than that of a 30-year-old with normal glucose tolerance, a difference that is clinically significant. Moreover, the specificity of HbA(1c) -based diagnostic criteria for prediabetes decreased substantially with increasing age (P<0.0001). CONCLUSIONS: In two large datasets, using different methods to measure HbA(1c), the association of age with higher HbA(1c) levels: was consistent and similar; was both statistically and clinically significant; was unexplained by features of aging; and reduced diagnostic specificity. Age should be taken into consideration when using HbA(1c) for the diagnosis and management of diabetes and prediabetes.


Assuntos
Envelhecimento/sangue , Glicemia/análise , Hemoglobinas Glicadas/análise , Resistência à Insulina , Regulação para Cima , Adulto , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/metabolismo , Estudos Transversais , Feminino , Intolerância à Glucose/sangue , Intolerância à Glucose/diagnóstico , Intolerância à Glucose/epidemiologia , Intolerância à Glucose/metabolismo , Humanos , Hiperglicemia/sangue , Hiperglicemia/diagnóstico , Hiperglicemia/epidemiologia , Hiperglicemia/metabolismo , Masculino , Programas de Rastreamento , Pessoa de Meia-Idade , Inquéritos Nutricionais , Estado Pré-Diabético/sangue , Estado Pré-Diabético/diagnóstico , Estado Pré-Diabético/epidemiologia , Estado Pré-Diabético/metabolismo , Prevalência , Sensibilidade e Especificidade , Estados Unidos/epidemiologia
5.
Rev Sci Instrum ; 95(6)2024 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-38912911

RESUMO

Penumbral imaging is a technique used in plasma diagnostics in which a radiation source shines through one or more large apertures onto a detector. To interpret a penumbral image, one must reconstruct it to recover the original source. The inferred source always has some error due to noise in the image and uncertainty in the instrument geometry. Interpreting the inferred source thus requires quantification of that inference's uncertainty. Markov chain Monte Carlo algorithms have been used to quantify uncertainty for similar problems but have never been used for the inference of the shape of an image. Because of this, there are no commonly accepted ways of visualizing uncertainty in two-dimensional data. This paper demonstrates the application of the Hamiltonian Monte Carlo algorithm to the reconstruction of penumbral images of fusion implosions and presents ways to visualize the uncertainty in the reconstructed source. This methodology enables more rigorous analysis of penumbral images than has been done in the past.

6.
Rev Sci Instrum ; 95(10)2024 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-39360876

RESUMO

Measurement of proton spectra is an important diagnostic for a variety of high energy density physics experiments. Current diagnostics are either not designed to capture the spectrum of low-energy protons or are unsuitable for high debris experiments. To bridge the gap, a new CR-39 based compact magnetic spectrometer (MagSpec) has been developed to measure proton spectra in the 1-20 MeV energy range, with a particular focus on the low-energy (1-6 MeV) spectrum, for use in experiments at the OMEGA Laser Facility and the National Ignition Facility (NIF). In the MagSpec diagnostic, protons of different energies are dispersed as they pass through a magnetic field before impinging on a differentially filtered CR-39 surface, resulting in a spatial distribution of CR-39 tracks that corresponds to the energy spectrum. In this paper, we discuss details of the design and implementation of MagSpec on the NIF and OMEGA.

7.
Rev Sci Instrum ; 95(9)2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39302171

RESUMO

Radiochromic film (RCF) and image plates (IPs) are both commonly used detectors in diagnostics fielded at inertial confinement fusion (ICF) and high-energy-density physics (HEDP) research facilities. Due to the intense x-ray background in all ICF/HEDP experiments, accurately calibrating the optical density of RCF as a function of x-ray dose, and the photostimulated luminescence per photon of IPs as a function of x-ray energy, is necessary for interpreting experimental results. Various measurements of the sensitivity curve of different IPs to x rays have been performed [Izumi et al., Proc. SPIE 8850, 885006 (2013) and Rosenberg et al., Rev. Sci. Instrum. 90(1), 013506 (2019)]; however, calibrating RCF is a tedious process that depends on factors such as the orientation in which the RCF is scanned in the film scanner and the batch of RCF used. These issues can be mitigated by cross-calibrating RCF with IPs to enable the use of IPs for the determination of dose on the RCF without scanning the RCF. Here, the first cross-calibration of RCF with IPs to quasi-monoenergetic titanium, copper, and molybdenum K-line x rays is presented. It is found that the IP-inferred dose rates on the RCF for the Ti and Mo x rays agree well with the measured dose rates, while the IP-inferred dose rate for the Cu x rays is larger than the measured dose rate by ∼2×. Explanations for this discrepancy and plans for future work are discussed.

8.
Rev Sci Instrum ; 95(10)2024 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-39356191

RESUMO

This paper reports on investigations on the impact of higher neutron fluences on the detection efficiency of protons with CR-39, a charged particle track detector. CR-39 is widely used as a diagnostic for inertial fusion applications and is an integral component of numerous particle diagnostics at the OMEGA laser facility and National Ignition Facility. As experiments continue to produce higher and higher yields, existing diagnostics are impacted by higher particle fluences than they were originally designed for. This paper presents data from experiments measuring proton signal on pieces of CR-39 with different levels of neutron fluence with two different etch times. The experiments show a decrease in signal recovery with increased neutron fluence, which is exacerbated at longer etch times. At 3 h etch time, data suggest a 17% ± 7% signal loss at 1.3 × 105 neutron-induced tracks per cm2 and a 67% ± 21% loss at 6 h etch time. Careful signal isolation techniques can recover most of the proton tracks even with moderate neutron fluence.

9.
Rev Sci Instrum ; 95(9)2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39315911

RESUMO

Image plates (IPs), or phosphor storage screens, are a technology employed frequently in inertial confinement fusion (ICF) and high energy density plasma (HEDP) diagnostics because of their sensitivity to many types of radiation, including, x rays, protons, alphas, beta particles, and neutrons. Prior studies characterizing IPs are predicated on the signal level remaining below the scanner saturation threshold. Since the scanning process removes some signal from the IP via photostimulated luminescence, repeatedly scanning an IP can bring the signal level below the scanner saturation threshold. This process, in turn, raises concerns about the signal response of IPs after an arbitrary number of scans and whether such a process yields, for example, a constant ratio of signal between the nth and n + 1st scan. Here, the sensitivity of IPs is investigated when scanned multiple times. It is demonstrated that the ratio of signal decay is not a constant with the number of scans and that the signal decay depends on the x-ray energy. As such, repeatedly scanning an IP with a mixture of signal types (e.g., x ray, neutron, and protons) enables ICF and HEDP diagnostics employing IPs to better isolate a particular signal type.

10.
Rev Sci Instrum ; 95(9)2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39315912

RESUMO

Image plates (IPs) are a quickly recoverable and reusable radiation detector often used to measure proton and x-ray fluence in laser-driven experiments. Recently, IPs have been used in a proton radiography detector stack on the OMEGA laser, a diagnostic historically implemented with CR-39, or radiochromic film. The IPs used in this and other diagnostics detect charged particles, neutrons, and x-rays indiscriminately. IPs detect radiation using a photo-stimulated luminescence (PSL) material, often phosphor, in which electrons are excited to metastable states by ionizing radiation. Protons at MeV energies deposit energy deeper into the IP compared with x rays below ∼20 keV due to the Bragg peak present for protons. This property is exploited to discriminate between radiation types. Doses of mono-energetic protons between 1.7 and 14 MeV are applied to IPs using the MIT linear electrostatic ion accelerator. This paper presents the results from consecutive scans of IPs irradiated with different proton energies. The PSL ratios between subsequent scans are shown to depend on proton energy, with higher energy protons having lower PSL ratios for each scan. This finding is separate from the known energy dependence in the absolute sensitivity of IPs. The results can be compared to complimentary work on x rays, showing a difference between protons and x rays, forging a path to discriminate between proton and x-ray fluence in mixed radiation environments.

11.
Int J Clin Pract ; 66(4): 369-73, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22356249

RESUMO

PURPOSE: The aim of this study was to evaluate if men with varying degrees of bother from a similar number of nocturia episodes differ with respect to self-rated sleep characteristics and fatigue. MATERIALS AND METHODS: As part of the baseline assessments during a nocturia treatment trial, 55 participants reported frequency and bother of nocturia using the AUA Symptom Inventory and completed 7-day sleep diaries prior to treatment. Participants who reported moderate nocturia (either two or three episodes nightly) were further grouped into categories of LOW (nocturia is no problem or a very small problem) or HIGH bother (nocturia is a big problem). Information from the participant completed sleep diaries was abstracted, including information on daytime napping, total sleep time, mean time needed to return to sleep, nighttime ratings of fatigue, and daytime ratings of fatigue. RESULTS: Of the 55 individuals who completed the pilot study, 24 study participants reported two or three episodes of nocturia and had either HIGH (n = 11) or LOW (n = 13) bother. Participants categorised with HIGH bother were significantly more likely than those with LOW bother to report difficulty initiating sleep (47.7 ± 34.4 vs. 23.5 ± 13.6 min, p = 0.05), difficulty returning to sleep after an awakening (28.9 ± 16.1 vs. 15.4 ± 9.6 min, p = 0.03) and greater morning fatigue (3.3 ± 0.7 vs. 2.5 ± 1.0, p = 0.04 on a 7-point scale). CONCLUSIONS: Since bother related to nocturia is linked to sleep quality, interventions targeting fatigue and sleep maintenance may provide useful targets in the management of nocturia in men.


Assuntos
Fadiga/etiologia , Noctúria/complicações , Transtornos do Sono-Vigília/etiologia , Idoso , Autoavaliação Diagnóstica , Fadiga/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Noctúria/tratamento farmacológico , Noctúria/fisiopatologia , Projetos Piloto , Qualidade de Vida , Autorrelato , Distúrbios do Início e da Manutenção do Sono/etiologia , Micção/fisiologia , Urodinâmica/fisiologia
12.
Phys Rev E ; 105(6): L063202, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35854613

RESUMO

In laser-produced high-energy-density plasmas, large-scale strong magnetic fields are spontaneously generated by the Biermann battery effects when temperature and density gradients are misaligned. Saturation of the magnetic field takes place when convection and dissipation balance field generation. While theoretical and numerical modeling provide useful insight into the saturation mechanisms, experimental demonstration remains elusive. In this letter, we report an experiment on the saturation dynamics and scaling of Biermann battery magnetic field in the regime where plasma convection dominates. With time-gated charged-particle radiography and time-resolved Thomson scattering, the field structure and evolution as well as corresponding plasma conditions are measured. In these conditions, the spatially resolved magnetic fields are reconstructed, leading to a picture of field saturation with a scaling of B∼1/L_{T} for a convectively dominated plasma, a regime where the temperature gradient scale (L_{T}) exceeds the ion skin depth.

13.
Rev Sci Instrum ; 93(8): 083511, 2022 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-36050092

RESUMO

The time-resolving magnetic recoil spectrometer (MRSt) is a transformative diagnostic that will be used to measure the time-resolved neutron spectrum from an inertial confinement fusion implosion at the National Ignition Facility (NIF). It uses a CD foil on the outside of the hohlraum to convert fusion neutrons to recoil deuterons. An ion-optical system positioned outside the NIF target chamber energy-disperses and focuses forward-scattered deuterons. A pulse-dilation drift tube (PDDT) subsequently dilates, un-skews, and detects the signal. While the foil and ion-optical system have been designed, the PDDT requires more development before it can be implemented. Therefore, a phased plan is presented that first uses the foil and ion-optical systems with detectors that can be implemented immediately-namely CR-39 and hDISC streak cameras. These detectors will allow the MRSt to be commissioned in an intermediate stage and begin collecting data on a reduced timescale, while the PDDT is developed in parallel. A CR-39 detector will be used in phase 1 for the measurement of the time-integrated neutron spectra with excellent energy-resolution, necessary for the energy calibration of the system. Streak cameras will be used in phase 2 for measurement of the time-resolved spectrum with limited spectral coverage, which is sufficient to diagnose the time-resolved ion temperature. Simulations are presented that predict the performance of the streak camera detector, indicating that it will achieve excellent burn history measurements at current yields, and good time-resolved ion-temperature measurements at yields above 3 × 1017. The PDDT will be used for optimal efficiency and resolution in phase 3.

14.
Rev Sci Instrum ; 93(8): 083513, 2022 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-36050054

RESUMO

Recent progress at the National Ignition Facility (NIF), with neutron yields of order 1 × 1017, places new constraints on diagnostics used to characterize implosion performance. The Magnetic Recoil neutron Spectrometer (MRS), which is routinely used to measure yield, ion temperature (Tion), and down-scatter ratio (dsr), has been adapted to allow measurements of dsr up to 5 × 1017, and yield and Tion up to 2 × 1018 in the near term with new data processing techniques and conversion foil solutions. This paper presents a solution for extending MRS operation up to a yield of 2 × 1019 (60 MJ) by moving the spectrometer outside of the NIF shield wall. This will not only enhance the upper yield limit by 10× but also improve signal-to-background by 5×.

15.
Rev Sci Instrum ; 93(11): 113534, 2022 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-36461490

RESUMO

Charged particle spectrometry is a critical diagnostic to study inertial-confinement-fusion plasmas and high energy density plasmas. The OMEGA Laser Facility has two fixed magnetic charged particle spectrometers (CPSs) to measure MeV-ions. In situ calibration of these spectrometers was carried out using 241Am and 226Ra alpha emitters. The alpha emission spectrum from the sources was measured independently using surface-barrier detectors (SBDs). The energy dispersion and broadening of the CPS systems were determined by comparing the CPS measured alpha spectrum to that of the SBD. The calibration method significantly constrains the energy dispersion, which was previously obtained through the measurement of charged particle fusion products. Overall, a small shift of 100 keV was observed between previous and the calibration done in this work.

17.
Rev Sci Instrum ; 92(1): 013504, 2021 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-33514215

RESUMO

This paper presents data from experiments with protons at non-normal incidence to CR-39 nuclear track detectors, analyzing the properties of detection efficiency, proton track diameter, track contrast, and track eccentricity. Understanding the CR-39 response to protons incident at an angle is important for designing charged particle detectors for inertial confinement fusion (ICF) applications. This study considers protons with incident energies less than 3 MeV. In this regime, an incident angle of 10° has no effect on CR-39 detection efficiency, and >85% detection efficiency is preserved up through 25° in the range of 1.0 MeV-2.1 MeV. For ICF applications, incident angles above 30° are deemed impractical for detector design due to significant drops in proton detection at all energies. We observe significant reductions in detection efficiency compared to theoretical predictions, particularly at low energies where proton tracks are etched away. The proton track diameter measured by the scan system is observed to decrease with higher incident angles. The track diameters are analyzed with two fitting models, and it is shown that the diameter-energy relation can be fit with the existing models at angles up to 30°. The optical contrast of the tracks tends to increase with the angle, meaning that the tracks are fainter, and a larger increase is observed for higher energies. Eccentricity, a measure of how elongated proton tracks are, increases with the incident angle and drops after the critical angle. The lowest energy tracks remain nearly circular even at higher angles.

18.
Rev Sci Instrum ; 92(4): 043551, 2021 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-34243410

RESUMO

Mono-energetic proton radiography is a vital diagnostic for numerous high-energy-density-physics, inertial-confinement-fusion, and laboratory-astrophysics experiments at OMEGA. With a large number of campaigns executing hundreds of shots, general trends in D3He backlighter performance are statistically observed. Each experimental configuration uses a different number of beams and drive symmetry, causing the backlighter to perform differently. Here, we analyze the impact of these variables on the overall performance of the D3He backlighter for proton-radiography studies. This study finds that increasing laser drive asymmetry can degrade the performance of the D3He backlighter. The results of this study can be used to help experimental designs that use proton radiography.

19.
Rev Sci Instrum ; 92(6): 063502, 2021 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-34243553

RESUMO

We report on the design and implementation of a new system used to characterize the energy-dependent x-ray transmission curve, Θ(E), through filters used in high-energy density physics diagnostics. Using an Amptek X-123-CdTe x-ray spectrometer together with a partially depleted silicon surface barrier detector, both the energy spectrum and total emission of an x-ray source have been accurately measured. By coupling these detectors with a custom PROTO-XRD x-ray source with interchangeable cathodes, accurate characterizations of Θ(E) for filters of varying materials and thicknesses have been obtained. The validity of the technique has been confirmed by accurately reproducing areal densities for high-purity filters with known x-ray transmission properties. In this paper, the experimental setup is described and the results of absorption calibrations performed on a variety of different filters are presented.

20.
Rev Sci Instrum ; 92(8): 083506, 2021 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-34470381

RESUMO

New designs and a new analysis technique have been developed for an existing compact charged-particle spectrometer on the NIF and OMEGA. The new analysis technique extends the capabilities of this diagnostic to measure arbitrarily shaped ion spectra down to 1 MeV with yields as low as 106. Three different designs are provided optimized for the measurement of DD protons, T3He deuterons, and 3He3He protons. The designs are highly customizable, and a generalized framework is provided for optimizing the design for alternative applications. Additionally, the understanding of the detector's response and uncertainties is greatly expanded upon. A new calibration procedure is also developed to increase the precision of the measurements.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA