Detalhe da pesquisa
1.
High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD.
EMBO J
; 42(12): e111272, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37143403
2.
Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges.
Adv Exp Med Biol
; 1389: 1-19, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350504
3.
Enzymology of Mammalian DNA Methyltransferases.
Adv Exp Med Biol
; 1389: 69-110, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350507
4.
A solid-phase transfection platform for arrayed CRISPR screens.
Mol Syst Biol
; 15(12): e8983, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31885201
5.
The DNMT3A R882H mutant displays altered flanking sequence preferences.
Nucleic Acids Res
; 46(6): 3130-3139, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29518238
6.
Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2.
Nucleic Acids Res
; 46(17): 9044-9056, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30102379
7.
Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.
Nucleic Acids Res
; 45(4): 1703-1713, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899645
8.
New concepts in DNA methylation.
Trends Biochem Sci
; 39(7): 310-8, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947342
9.
Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm.
Nucleic Acids Res
; 44(18): 8556-8575, 2016 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27521372
10.
Application of histone modification-specific interaction domains as an alternative to antibodies.
Genome Res
; 24(11): 1842-53, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25301795
11.
A solid-phase transfection platform for arrayed CRISPR screens.
Mol Syst Biol
; 16(6): e9611, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33438803
12.
Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges.
Adv Exp Med Biol
; 945: 1-17, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27826832
13.
Enzymology of Mammalian DNA Methyltransferases.
Adv Exp Med Biol
; 945: 87-122, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27826836
14.
The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.
J Biol Chem
; 289(7): 4106-15, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24368767
15.
Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase.
J Biol Chem
; 289(43): 29602-13, 2014 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25147181
16.
Cyclical DNA methylation of a transcriptionally active promoter.
Nature
; 452(7183): 45-50, 2008 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-18322525
17.
Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation.
Nucleic Acids Res
; 40(2): 569-80, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21926161
18.
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.
Nature
; 449(7159): 248-51, 2007 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17713477
19.
Genomic imprinting--the struggle of the genders at the molecular level.
Angew Chem Int Ed Engl
; 52(51): 13524-36, 2013 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24346936
20.
EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells.
Front Endocrinol (Lausanne)
; 14: 1134478, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37008919