Detalhe da pesquisa
1.
AAV9-mediated SH3TC2 gene replacement therapy targeted to Schwann cells for the treatment of CMT4C.
Mol Ther
; 31(11): 3290-3307, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37641403
2.
Charcot-Marie-Tooth neuropathies: Current gene therapy advances and the route toward translation.
J Peripher Nerv Syst
; 28(2): 150-168, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36965137
3.
NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice.
Brain
; 145(11): 3999-4015, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35148379
4.
AAV9-mediated Schwann cell-targeted gene therapy rescues a model of demyelinating neuropathy.
Gene Ther
; 28(10-11): 659-675, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33692503
5.
Emerging Therapies for Charcot-Marie-Tooth Inherited Neuropathies.
Int J Mol Sci
; 22(11)2021 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34205075
6.
Aberrant Mitochondrial Dynamics and Exacerbated Response to Neuroinflammation in a Novel Mouse Model of CMT2A.
Int J Mol Sci
; 22(21)2021 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769001
7.
Gene replacement therapy in a model of Charcot-Marie-Tooth 4C neuropathy.
Brain
; 142(5): 1227-1241, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30907403
8.
Golgi-retained Cx32 mutants interfere with gene addition therapy for CMT1X.
Hum Mol Genet
; 26(9): 1622-1633, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334782
9.
Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.
Proc Natl Acad Sci U S A
; 113(17): E2421-9, 2016 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27035961
10.
Gene therapy targeting oligodendrocytes provides therapeutic benefit in a leukodystrophy model.
Brain
; 140(3): 599-616, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100454
11.
Transgenic replacement of Cx32 in gap junction-deficient oligodendrocytes rescues the phenotype of a hypomyelinating leukodystrophy model.
Hum Mol Genet
; 24(7): 2049-64, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25524707
12.
Intraneural GJB1 gene delivery improves nerve pathology in a model of X-linked Charcot-Marie-Tooth disease.
Ann Neurol
; 78(2): 303-16, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26010264
13.
Gene delivery targeted to oligodendrocytes using a lentiviral vector.
J Gene Med
; 16(11-12): 364-73, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25394283
14.
Assessing the permeability of the rat sciatic nerve epineural sheath against compounds with local anesthetic activity: an ex vivo electrophysiological study.
Toxicol Mech Methods
; 23(8): 634-40, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23862572
15.
Gene replacement therapy in two Golgi-retained CMT1X mutants before and after the onset of demyelinating neuropathy.
Mol Ther Methods Clin Dev
; 30: 377-393, 2023 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37645436
16.
A translatable RNAi-driven gene therapy silences PMP22/Pmp22 genes and improves neuropathy in CMT1A mice.
J Clin Invest
; 132(13)2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35579942
17.
Pharmacological activation of the C5a receptor leads to stimulation of the ß-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer's disease.
Front Immunol
; 13: 947071, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36091045
18.
High concentrations of dichloroacetate have minor effects on the vitality of the mammalian nerve fibers: an ex-vivo electrophysiological study.
Anticancer Drugs
; 22(3): 273-6, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21183852
19.
Assessing the local anesthetic effect of five essential oil constituents.
Planta Med
; 76(15): 1647-53, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20506076
20.
Gene therapy approaches targeting Schwann cells for demyelinating neuropathies.
Brain Res
; 1728: 146572, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31790684