Detalhe da pesquisa
1.
PVT1 interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma.
Haematologica
; 109(2): 567-577, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37496441
2.
A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment.
Hum Mutat
; 37(9): 964-75, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27328812
3.
The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma.
Front Oncol
; 13: 1303677, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38148842
4.
Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma.
Cancer Res
; 82(24): 4586-4603, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36219398
5.
One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies.
Epigenomes
; 5(4)2021 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34968247
6.
A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma.
Cell Death Dis
; 12(2): 167, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579905
7.
EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions.
Oncotarget
; 8(6): 10213-10224, 2017 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28052011
8.
The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomains.
Oncotarget
; 8(61): 103731-103743, 2017 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29262596
9.
Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.
Oncotarget
; 7(6): 6809-23, 2016 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26755663
10.
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.
J Exp Med
; 212(6): 833-43, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25987724
11.
AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and dose dependent reduction of tyrosine kinase activity in acute myeloid leukemia.
Biochem Pharmacol
; 87(2): 284-91, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24200998
12.
Polycomb target genes are silenced in multiple myeloma.
PLoS One
; 5(7): e11483, 2010 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20634887
13.
Mutation screening of the SMARCA3 gene in Swedish colorectal cancer patients.
Mol Med Rep
; 1(2): 263-8, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-21479407