Detalhe da pesquisa
1.
The Tmod cellular logic gate as a solution for tumor-selective immunotherapy.
Clin Immunol
; 241: 109030, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35561999
2.
A rational approach to assess off-target reactivity of a dual-signal integrator for T cell therapy.
Toxicol Appl Pharmacol
; 437: 115894, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35085592
3.
NOT gated T cells that selectively target EGFR and other widely expressed tumor antigens.
iScience
; 27(6): 109913, 2024 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38799557
4.
Geometric parameters that affect the behavior of logic-gated CAR T cells.
Front Immunol
; 15: 1304765, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343543
5.
Robust In Vitro Pharmacology of Tmod, a Synthetic Dual-Signal Integrator for Cancer Cell Therapy.
Front Immunol
; 13: 826747, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35359952
6.
HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
Mol Ther Oncolytics
; 27: 157-166, 2022 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36381658
7.
Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity.
Cancer Res Commun
; 2(1): 58-65, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36860694
8.
Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells.
J Immunother Cancer
; 10(1)2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091455
9.
A carcinoembryonic antigen-specific cell therapy selectively targets tumor cells with HLA loss of heterozygosity in vitro and in vivo.
Sci Transl Med
; 14(634): eabm0306, 2022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235342
10.
Next-generation sequencing and its potential impact.
Chem Res Toxicol
; 24(8): 1163-8, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21630708
11.
Design of TCR Structural Variants That Retain or Invert the Normal Activation Signal.
Immunohorizons
; 5(5): 349-359, 2021 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34039676
12.
Extensive functional comparisons between chimeric antigen receptors and T cell receptors highlight fundamental similarities.
Mol Immunol
; 138: 137-149, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34419823
13.
Re-examination of MAGE-A3 as a T-cell Therapeutic Target.
J Immunother
; 44(3): 95-105, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33284140
14.
Potent, Selective CARs as Potential T-Cell Therapeutics for HPV-positive Cancers.
J Immunother
; 44(8): 292-306, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34432728
15.
Why is cancer drug discovery so difficult?
Nat Rev Drug Discov
; 6(2): 115-20, 2007 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17159925
16.
Cancer T-cell therapy: building the foundation for a cure.
F1000Res
; 9: 1295, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33335718
17.
A multivariate, quantitative assay that disentangles key kinetic parameters of primary human T cell function in vitro.
PLoS One
; 15(11): e0241421, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33166305
18.
Engineered T cells directed at tumors with defined allelic loss.
Mol Immunol
; 128: 298-310, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33012527
19.
Structure-function relationships of chimeric antigen receptors in acute T cell responses to antigen.
Mol Immunol
; 126: 56-64, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32768859
20.
Single variable domains from the T cell receptor ß chain function as mono- and bifunctional CARs and TCRs.
Sci Rep
; 9(1): 17291, 2019 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31754147