RESUMO
Circadian rhythms in urinary catecholamine excretion, performance and self-ratings were studied in two experiments with a total of 29 subjects who were deprived of sleep for 72 hr. Adrenaline excretion and fatigue ratings showed the most consistent circadian variations; noradrenaline and performance rhythms were more irregular. The average crest phase for adrenaline excretion was around 1400 hr, for noradrenaline about 0800 hr, for performance 1700 hr and for fatigue 0500 hr. Twenty-four hour levels of performance and 'subjective arousal' decreased over the three days of sleep deprivation, while adrenaline excretion levels increased.
Assuntos
Catecolaminas/urina , Ritmo Circadiano , Privação do Sono , Análise e Desempenho de Tarefas , Adulto , Nível de Alerta , Epinefrina/urina , Fadiga/etiologia , Humanos , Masculino , Norepinefrina/urina , Autoavaliação (Psicologia) , Estresse Psicológico , Fatores de TempoAssuntos
Epinefrina/urina , Norepinefrina/urina , Autoanálise , Di-Hidroxifenilalanina/urina , Estabilidade de Medicamentos , Estudos de Avaliação como Assunto , Humanos , Concentração de Íons de Hidrogênio , Indicadores e Reagentes , Indóis , Matemática , Métodos , Metildopa/urina , Microquímica , Espectrometria de Fluorescência , Espectrofotometria Ultravioleta , Fatores de TempoAssuntos
Saúde Ambiental , Doenças Profissionais/etiologia , Transtornos Psicofisiológicos/etiologia , Estresse Fisiológico/complicações , Estresse Psicológico/complicações , Adaptação Fisiológica , Adaptação Psicológica , Adulto , Sedimentação Sanguínea , Catecolaminas/urina , Fadiga/etiologia , Feminino , Coração/fisiopatologia , Humanos , Ferro/sangue , Masculino , Pessoa de Meia-Idade , Medicina Militar , Medicina do Trabalho , Testes de Função TireóideaRESUMO
The effect of a 75-hour vigil on the erythrocyte sedimentation rate (ESR), i.a., was studied in two experiments with 63 healthy male volunteers. The ESR was increased at the end of the vigil compared with pre-exposure values. The increases did not correlate significantly with concomitant changes in serum triglycerides, free fatty acids, cholesterol or gammaglobulins, except for a significant, negative correlation with cholesterol changes in one of the two studies. Although the mechanism for the increases in ESR in response to stressor exposure remains unclear, it is concluded that when using the ESR in clinical practice, allowance should be made for situational factors such as the patient having experienced some stressful days and sleepless nights.