Detalhe da pesquisa
1.
Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia.
Blood
; 138(1): 44-56, 2021 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33684943
2.
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Nature
; 542(7642): 489-493, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199309
3.
MYD88 L265P mutations identify a prognostic gene expression signature and a pathway for targeted inhibition in CLL.
Br J Haematol
; 184(6): 925-936, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30537114
4.
Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity.
Blood
; 128(2): 195-203, 2016 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27247136
5.
An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR-T and TCR-T Cellular Therapies Development.
Clin Pharmacol Ther
; 115(2): 188-200, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37983584
6.
MicroRNAs and induced pluripotent stem cells for human disease mouse modeling.
J Biomed Biotechnol
; 2012: 758169, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22619497
7.
Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course.
Front Oncol
; 11: 640731, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34113563
8.
TLR7 and TLR8 Differentially Activate the IRF and NF-κB Pathways in Specific Cell Types to Promote Inflammation.
Immunohorizons
; 4(2): 93-107, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086319
9.
Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia.
Cancer Cell
; 34(6): 982-995.e7, 2018 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503705
10.
Voxtalisib (XL765) in patients with relapsed or refractory non-Hodgkin lymphoma or chronic lymphocytic leukaemia: an open-label, phase 2 trial.
Lancet Haematol
; 5(4): e170-e180, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29550382
11.
Survival of Del17p CLL Depends on Genomic Complexity and Somatic Mutation.
Clin Cancer Res
; 23(3): 735-745, 2017 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27503198
12.
Role of mir-15a/16-1 in early B cell development in a mouse model of chronic lymphocytic leukemia.
Oncotarget
; 7(38): 60986-60999, 2016 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27533467
13.
Alterations in the mir-15a/16-1 Loci Impairs Its Processing and Augments B-1 Expansion in De Novo Mouse Model of Chronic Lymphocytic Leukemia (CLL).
PLoS One
; 11(3): e0149331, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26959643
14.
Phase I Trial of the Pan-PI3K Inhibitor Pilaralisib (SAR245408/XL147) in Patients with Chronic Lymphocytic Leukemia (CLL) or Relapsed/Refractory Lymphoma.
Clin Cancer Res
; 21(14): 3160-9, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25840972
15.
Minimal residual disease detected by immunoglobulin sequencing predicts CLL relapse more effectively than flow cytometry.
Leuk Lymphoma
; 59(8): 1986-1989, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29164966
16.
MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders.
Leuk Res Treatment
; 2012: 603830, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23259069
17.
Role of microRNA-15a in autoantibody production in interferon-augmented murine model of lupus.
Mol Immunol
; 52(2): 61-70, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22578383