RESUMO
Postmortem lung pathology of a patient in Japan with severe acute respiratory syndrome coronavirus 2 infection showed diffuse alveolar damage as well as bronchopneumonia caused by Streptococcus pneumoniae infection. The distribution of each pathogen and the accompanying histopathology suggested the infections progressed in a mutually exclusive manner within the lung, resulting in fatal respiratory failure.
Assuntos
COVID-19/patologia , Coinfecção , Pulmão , Infecções Pneumocócicas/patologia , Idoso de 80 Anos ou mais , Autopsia , Humanos , Pulmão/microbiologia , Pulmão/patologia , Pulmão/virologia , Masculino , SARS-CoV-2/isolamento & purificação , Streptococcus pneumoniae/isolamento & purificaçãoRESUMO
BACKGROUND: Although the functional merits of preserving cervical nerves in neck dissection for head and neck cancer have been reported, the oncologic safety has not yet been determined. Therefore, the purpose of this study was to evaluate the safety of cervical nerve preservation. METHODS: A retrospective chart review was performed on patients with head and neck cancer who had been treated by neck dissection between 2009 and 2014 at Kyoto Medical Center. Management of cervical nerves and clinical results were analyzed. RESULTS: A total of 335 sides of neck dissection had been performed in 222 patients. Cervical nerves were preserved in 175 neck sides and resected in 160 sides. The 5-year overall survival (OS) rate calculated by the Kaplan-Meier method was 71%. The 5-year neck control rate was 95% in cervical nerve preserved sides and 89% in cervical nerve resected sides. CONCLUSION: Preserving cervical nerves in neck dissection is oncologically safe in selected cases.