Detalhe da pesquisa
1.
C9orf72-associated dipeptide protein repeats form A11-positive oligomers in amyotrophic lateral sclerosis and frontotemporal dementia.
J Biol Chem
; 300(2): 105628, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38295729
2.
NLRP3 inflammasome activation drives tau pathology.
Nature
; 575(7784): 669-673, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748742
3.
Flanking regions, amyloid cores, and polymorphism: the potential interplay underlying structural diversity.
J Biol Chem
; 299(9): 105122, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37536631
4.
Big tau aggregation disrupts microtubule tyrosination and causes myocardial diastolic dysfunction: from discovery to therapy.
Eur Heart J
; 44(17): 1560-1570, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37122097
5.
Senescence, brain inflammation, and oligomeric tau drive cognitive decline in Alzheimer's disease: Evidence from clinical and preclinical studies.
Alzheimers Dement
; 20(1): 709-727, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37814508
6.
Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein.
J Biol Chem
; 298(11): 102498, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36116552
7.
Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer's disease.
J Biol Chem
; 298(4): 101766, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35202653
8.
Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics.
Proteins
; 2023 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37530227
9.
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.
Chem Rev
; 121(4): 2545-2647, 2021 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33543942
10.
Aß/tau oligomer interplay at human synapses supports shifting therapeutic targets for Alzheimer's disease.
Cell Mol Life Sci
; 79(4): 222, 2022 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377002
11.
Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles.
Biochemistry
; 61(17): 1766-1773, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001818
12.
Infectious etiology and amyloidosis in Alzheimer's disease: The puzzle continues.
J Biol Chem
; 297(2): 100936, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34217702
13.
The amyloid concentric ß-barrel hypothesis: Models of amyloid beta 42 oligomers and annular protofibrils.
Proteins
; 90(5): 1190-1209, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35038191
14.
Longitudinal characterization of retinal vasculature alterations with optical coherence tomography angiography in a mouse model of tauopathy.
Exp Eye Res
; 224: 109240, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36096190
15.
Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons.
Brain
; 144(1): 288-309, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33246331
16.
Modulating disease-relevant tau oligomeric strains by small molecules.
J Biol Chem
; 295(44): 14807-14825, 2020 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737202
17.
Tau induces formation of α-synuclein filaments with distinct molecular conformations.
Biochem Biophys Res Commun
; 554: 145-150, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33798940
18.
Advances and considerations in AD tau-targeted immunotherapy.
Neurobiol Dis
; 134: 104707, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31841678
19.
TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
Neurobiol Dis
; 146: 105130, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33065281
20.
Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
Proc Natl Acad Sci U S A
; 114(23): E4648-E4657, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533388