Detalhe da pesquisa
1.
Combination of pimitespib (TAS-116) with sunitinib is an effective therapy for imatinib-resistant gastrointestinal stromal tumors.
Int J Cancer
; 152(12): 2580-2593, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36752576
2.
Discovery of Futibatinib: The First Covalent FGFR Kinase Inhibitor in Clinical Use.
ACS Med Chem Lett
; 14(4): 396-404, 2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37077386
3.
1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo.
Int J Oncol
; 34(5): 1373-80, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19360349
4.
TAS4464, A Highly Potent and Selective Inhibitor of NEDD8-Activating Enzyme, Suppresses Neddylation and Shows Antitumor Activity in Diverse Cancer Models.
Mol Cancer Ther
; 18(7): 1205-1216, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31092565
5.
Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil.
Oncol Rep
; 17(6): 1453-60, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17487404
6.
Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA.
Int J Oncol
; 46(6): 2327-34, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25901475
7.
Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models.
Oncol Rep
; 32(6): 2319-26, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25230742
8.
Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line.
Cancer Sci
; 96(5): 295-302, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15904471
9.
Cellular and biochemical mechanisms of the resistance of human cancer cells to a new anticancer ribo-nucleoside, TAS-106.
Jpn J Cancer Res
; 93(4): 445-52, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11985795
10.
Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2.
Jpn J Cancer Res
; 93(7): 825-33, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12149149