Detalhe da pesquisa
1.
Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.
Proc Natl Acad Sci U S A
; 116(9): 3703-3711, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30808757
2.
High-density lipoproteins are a potential therapeutic target for age-related macular degeneration.
J Biol Chem
; 295(39): 13601-13616, 2020 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737203
3.
Regulation of age-related macular degeneration-like pathology by complement factor H.
Proc Natl Acad Sci U S A
; 112(23): E3040-9, 2015 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25991857
4.
Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.
Am J Pathol
; 185(1): 29-42, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25447048
5.
The role of complement dysregulation in AMD mouse models.
Adv Exp Med Biol
; 801: 213-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24664701
6.
Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.
Proc Natl Acad Sci U S A
; 108(28): E279-87, 2011 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21690377
7.
AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model.
Invest Ophthalmol Vis Sci
; 64(10): 25, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37471073
8.
Polarized Desmosome and Hemidesmosome Shedding via Exosomes is an Early Indicator of Outer Blood-Retina Barrier Dysfunction.
bioRxiv
; 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398366
9.
Polarized Desmosome and Hemidesmosome Shedding via Small Extracellular Vesicles is an Early Indicator of Outer Blood-Retina Barrier Dysfunction.
J Extracell Biol
; 2(10)2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38108061
10.
Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration.
J Immunol
; 185(9): 5486-94, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20876352
11.
Oxidative stress-induced expression and modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in mammalian retina.
Biochim Biophys Acta
; 1773(9): 1473-82, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17673310
12.
Author Correction: Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers.
Sci Rep
; 8(1): 17327, 2018 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455433
13.
Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci
; 59(2): 662-673, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29392311
14.
Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers.
Sci Rep
; 7(1): 4901, 2017 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28687758
15.
Expression of the blue-light receptor cryptochrome in the human retina.
Invest Ophthalmol Vis Sci
; 44(10): 4515-21, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14507900
16.
Rapid and sensitive method for detection of Y402, H402, I62, and V62 variants of complement factor H in human plasma samples using mass spectrometry.
Invest Ophthalmol Vis Sci
; 50(4): 1540-5, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19029036