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1.
Opt Express ; 21(22): 26820-35, 2013 Nov 04.
Artigo em Inglês | MEDLINE | ID: mdl-24216904

RESUMO

To achieve an immersive natural 3D experience on a large screen, a 300-Mpixel multi-projection 3D display that has a 100-inch screen and a 40° viewing angle has been developed. To increase the number of rays emanating from each pixel to 300 in the horizontal direction, three hundred projectors were used. The projector configuration is an important issue in generating a high-quality 3D image, the luminance characteristics were analyzed and the design was optimized to minimize the variation in the brightness of projected images. The rows of the projector arrays were repeatedly changed according to a predetermined row interval and the projectors were arranged in an equi-angular pitch toward the constant central point. As a result, we acquired very smooth motion parallax images without discontinuity. There is no limit of viewing distance, so natural 3D images can be viewed from 2 m to over 20 m.

2.
J Toxicol Sci ; 37(2): 431-7, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22467034

RESUMO

The estrogenic activity of industrial chemicals, di(2-ethylhexyl) phthalate (DEHP), di(n-butyl) phthalate (DBP), benzylbutyl phthalate (BBP), diethyl phthalate (DEP), tetrabromobisphenol A (TBBPA), bisphenol A (BPA), and nonylphenol (NP), was compared using OECD test guideline 455(TG455), stably transfected transcriptional activation (STTA) and estrogen receptor (ER) binding assays. The estrogenic activity of BBP, BPA and NP were approximately 180,000-fold (PC(50), 4.32 x 10(-6 )M), 5,000-fold (PC(50), 1.26 x 10(-7) M) and 120,000-fold (PC(50), 2.92 x 10(-6 )M) less than 17ß-estradiol (PC(50), 2.43 x 10(-11)M), whereas DEHP, DBP and DEP did not show any estrogenicity activity in the STTA assay. Moreover, binding affinities to human ERα of BBP, BPA, and NP were approximately 200,000-fold (IC(50), 4.91 x 10(-4) M), 8000-fold (IC(50), 1.92 x 10(-5) M) and 1400-fold (IC(50), 3.34 x 10(-6) M) less than 17ß-estradiol (IC(50), 2.45 x 10(-9) M) in competitive human ERα binding assay. The relative potencies of STTA assay were very similar to ER binding, E-screen, and Yeast screening assays. Therefore, our results suggested that OECD test guideline TG455 may be useful as a screening test for potential endocrine disruptors.


Assuntos
Receptor alfa de Estrogênio/metabolismo , Estrogênios/metabolismo , Fenóis/metabolismo , Ácidos Ftálicos/metabolismo , Bifenil Polibromatos/toxicidade , Compostos Benzidrílicos , Ligação Competitiva , Bioensaio , Receptor alfa de Estrogênio/genética , Células HeLa , Humanos , Proteínas Recombinantes/metabolismo , Ativação Transcricional
3.
Toxicol Res ; 27(3): 181-4, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24278570

RESUMO

Screening of estrogenic activity on dichloro diphenyl trichloroethane (DDT), dichloro diphenyl dichloro ethylene (DDE), dieldrin, heptachlor, aldrin, chlordane, lindane, polybrominated diphenyl ethers (PBDE) and parabens was compared using Organization for Economic Cooperation and Development (OECD) test guideline 455 (TG455). The estrogenic activity of DDT was 58,000-fold (PC50, 1.67 × 10(-6) M) less than 17ß-estradiol(E2) (PC50, 2.88 × 10(-11) M) but DDE, dieldrin, heptachlor, aldrin, chlordane, lindane and PBDE did not show any estrogenic activity in this assay system. In the case of paraben compounds, the rank of relative transcriptional activation (logRTA) was butyl paraben -1.63752 (PC50, 1.25 × 10(-7)M) > isobutyl paraben -2.34008 (PC50, 6.3 × 10(-7)M) > ethyl paraben -2.64016 (PC50, 1.26 × 10(-6) M) > isopropyl paraben -2.73993 (PC50, 1.58 × 10(-6)M) > propyl paraben -2.84164 (PC50, 2.0 × 10(-6) M). Our data suggest that OECD test guideline TG455 may be useful as a screening tool for potential endocrine disruptors.

4.
J Opt Soc Am A Opt Image Sci Vis ; 25(9): 2215-22, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18758547

RESUMO

Display manufacturers require new data and computational models that consider the effect of ambient illumination in order to develop higher-quality displays. In this study, typical variations of small-sized mobile LCDs that exist in the real world were first simulated using a device characterization technique. In addition, psychophysical attributes (e.g., naturalness, clearness, sharpness, contrast, colorfulness, and preference) affecting the image quality evaluation process were analyzed. Consequently, naturalness and clearness were found to be the most statistically significant psychophysical attributes for modeling image quality. As the ambient-illumination level was increased, the image quality was exponentially impaired and the contribution of clearness increased.


Assuntos
Telefone Celular , Apresentação de Dados , Psicofísica/métodos , Adulto , Percepção de Cores , Desenho de Equipamento , Feminino , Humanos , Aumento da Imagem/instrumentação , Aumento da Imagem/métodos , Masculino , Variações Dependentes do Observador , Óptica e Fotônica , Desempenho Psicomotor , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Percepção Visual
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