Detalhe da pesquisa
1.
Covalent linkage of distinct substrate degrons controls assembly and disassembly of DegP proteolytic cages.
Cell
; 145(1): 67-78, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21458668
2.
A dual gene-specific mutator system installs all transition mutations at similar frequencies in vivo.
Nucleic Acids Res
; 51(10): e59, 2023 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37070179
3.
Development of a genome-targeting mutator for the adaptive evolution of microbial cells.
Nucleic Acids Res
; 50(7): e38, 2022 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34928386
4.
Discovery of Terminal Oxazole-Bearing Natural Products by a Targeted Metabologenomic Approach.
Angew Chem Int Ed Engl
; 63(21): e202402465, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38482567
5.
Exploring the Diverse Landscape of Biaryl-Containing Peptides Generated by Cytochrome P450 Macrocyclases.
J Am Chem Soc
; 145(40): 22047-22057, 2023 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37756205
6.
Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB.
Nat Chem Biol
; 17(11): 1123-1131, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475564
7.
Gene-specific mutagenesis enables rapid continuous evolution of enzymes in vivo.
Nucleic Acids Res
; 49(6): e32, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33406230
8.
Discovery and Biosynthesis of Cihunamides, Macrocyclic Antibacterial RiPPs with a Unique C-N Linkage Formed by CYP450 Catalysis.
Angew Chem Int Ed Engl
; 62(26): e202300998, 2023 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37114290
9.
Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N-Methyltransferases in Bacteria.
Biochemistry
; 61(3): 183-194, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35061348
10.
Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress.
Genes Dev
; 28(8): 902-11, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24736846
11.
Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer's Disease.
Molecules
; 27(24)2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36557811
12.
New developments in RiPP discovery, enzymology and engineering.
Nat Prod Rep
; 38(1): 130-239, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32935693
13.
Introduction of Bifunctionality into the Multidomain Architecture of the ω-Ester-Containing Peptide Plesiocin.
Biochemistry
; 59(3): 285-289, 2020 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31644266
14.
Genome Mining Reveals High Topological Diversity of ω-Ester-Containing Peptides and Divergent Evolution of ATP-Grasp Macrocyclases.
J Am Chem Soc
; 142(6): 3013-3023, 2020 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31961152
15.
A Topologically Distinct Modified Peptide with Multiple Bicyclic Core Motifs Expands the Diversity of Microviridin-Like Peptides.
Chembiochem
; 20(8): 1051-1059, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30576039
16.
A Small Periplasmic Protein with a Hydrophobic C-Terminal Residue Enhances DegP Proteolysis as a Suicide Activator.
J Bacteriol
; 200(3)2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947671
17.
Identification of Nucleophilic Probes for Protease-Mediated Transpeptidation.
Molecules
; 23(9)2018 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131476
18.
Enzymatic Cross-Linking of Side Chains Generates a Modified Peptide with Four Hairpin-like Bicyclic Repeats.
Biochemistry
; 56(37): 4927-4930, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28841794
19.
Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival.
Proc Natl Acad Sci U S A
; 109(19): 7263-8, 2012 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22529381
20.
Evolutionary Spread of Distinct O-methyltransferases Guides the Discovery of Unique Isoaspartate-Containing Peptides, Pamtides.
Adv Sci (Weinh)
; 11(2): e2305946, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37987032