Detalhe da pesquisa
1.
The Effect of Light and Dark Treatment on the Production of Rosmarinic Acid and Biological Activities in Perilla frutescens Microgreens.
Plants (Basel)
; 12(8)2023 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37111837
2.
CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs.
Drug Metab Dispos
; 38(12): 2100-4, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20847137
3.
Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects.
Drug Metab Dispos
; 37(9): 1895-903, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19541829
4.
Genetic variations and frequencies of major haplotypes in SLCO1B1 encoding the transporter OATP1B1 in Japanese subjects: SLCO1B1*17 is more prevalent than *15.
Drug Metab Pharmacokinet
; 22(6): 456-61, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18159134
5.
Fourteen novel genetic variations and haplotype structures of the TYMS gene encoding human thymidylate synthase (TS).
Drug Metab Pharmacokinet
; 21(6): 509-16, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17220568
6.
Thirty novel genetic variations in the SLC29A1 gene encoding human equilibrative nucleoside transporter 1 (hENT1).
Drug Metab Pharmacokinet
; 21(3): 248-56, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16858130
7.
Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin.
Clin Cancer Res
; 11(7): 2620-4, 2005 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15814642
8.
Upregulations of metallothionein gene expressions and tolerance to heavy metal toxicity by three dimensional cultivation of HepG2 cells on VECELL 3-D inserts.
J Toxicol Sci
; 41(1): 147-53, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26763402
9.
Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.
Cancer Chemother Pharmacol
; 56(5): 465-72, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15918040
10.
Light-dependent mutagenesis by benzo[a]pyrene is mediated via oxidative DNA damage.
Environ Mol Mutagen
; 46(3): 141-9, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15880422
11.
Modulation of oxidative mutagenesis and carcinogenesis by polymorphic forms of human DNA repair enzymes.
Mutat Res
; 591(1-2): 60-73, 2005 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16081110
12.
Single nucleotide polymorphisms and haplotype frequencies of CYP3A5 in a Japanese population.
Hum Mutat
; 21(6): 653, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-14961555
13.
Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2).
Drug Metab Pharmacokinet
; 18(5): 327-32, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-15618752
14.
Suppression of chemically induced and spontaneously occurring oxidative mutagenesis by three alleles of human OGG1 gene encoding 8-hydroxyguanine DNA glycosylase.
Mutat Res
; 554(1-2): 365-74, 2004 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15450432
15.
Comparative metabolome analysis of cultured fetal and adult hepatocytes in humans.
J Toxicol Sci
; 39(5): 717-23, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25242401
16.
Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms.
Clin Pharmacokinet
; 49(8): 549-58, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20608756
17.
Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients.
Cancer Chemother Pharmacol
; 66(1): 95-105, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19771428
18.
Genetic variations of the ABC transporter gene ABCB11 encoding the human bile salt export pump (BSEP) in a Japanese population.
Drug Metab Pharmacokinet
; 24(3): 277-81, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19571440
19.
Ethnic differences of two non-synonymous single nucleotide polymorphisms in CDA gene.
Drug Metab Pharmacokinet
; 24(6): 553-6, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-20045991
20.
Twenty novel genetic variations and haplotype structures of the DCK gene encoding human deoxycytidine kinase (dCK).
Drug Metab Pharmacokinet
; 23(5): 379-84, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18974616